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TRP Channel Classification

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Transient Receptor Potential Canonical Channels and Brain Diseases

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 976))

Abstract

The transient receptor potential (TRP) ion channels are named after the discovery of the photo-transducted channels in Drosophila. TRPs, activated by various extracellular and intracellular stimuli, play a plethora of physiological and pathological roles. There are seven families of TRPs including TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPP (polycystin), TRPML (mucolipin), and TRPN (Drosophila NOMPC) in mammals. In yeast, the eighth TRP family was recently identified and named as TRPY. We here briefly summarize the classification and function of TRP cation channel superfamily.

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  1. Columbia University Medical Center, New York, NY, 10032, USA

    Hongyu Li

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  1. Center of Cognition and Brain Science, Institute of Basic Medical Science, Beijing, China

    Yizheng Wang

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Li, H. (2017). TRP Channel Classification. In: Wang, Y. (eds) Transient Receptor Potential Canonical Channels and Brain Diseases. Advances in Experimental Medicine and Biology, vol 976. Springer, Dordrecht. https://doi.org/10.1007/978-94-024-1088-4_1

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