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The Effect on Blood Biochemical Factors of a ICR-Mice in a High-Fat Diet with Taurine 20%

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Taurine 10

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 975))

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Abstract

The purpose of this study was to examine the effects of taurine on lipid levels and liver function and the actions of insulin and leptin by biochemically analyzing the blood of albino mice fed a diet containing 20% taurine. The group fed a high-fat diet (HF) containing 20% taurine (HF + taurine 20%) showed higher blood HDL cholesterol levels as well as significantly lower total cholesterol and triglyceride levels (p < 0.05) than the group fed HF. No significant difference was observed among indicators of liver function, such as alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, and lactate dehydrogenase activities. However, the HF + taurine 20% group showed significantly lower insulin and leptin levels than the HF group (p < 0.05). These findings show that 20% taurine had a significant effect on blood lipid levels and blood sugar maintenance in mice fed an HF.

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Abbreviations

cAMP:

Cyclic AMP

HF:

High fat diet

HDL-cholesterol:

High density lipoprotein-cholesterol

LDL-cholesterol:

Low density lipoprotein-cholesterol

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Authors and Affiliations

  1. Department of Food and Nutrition, Sahmyook University, Seoul, 01795, South Korea

    Kyung-Ok Shin & Kyung-Soon Choi

  2. Department of Food Science, KC University, Seoul, 07661, South Korea

    Jin A. Yoon

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  1. Kyung-Ok Shin
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  2. Jin A. Yoon
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  3. Kyung-Soon Choi
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Correspondence to Kyung-Soon Choi .

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Editors and Affiliations

  1. Department of Life Sciences, University of Seoul, Seoul, South Korea

    Dong-Hee Lee  & Ha Won Kim  & 

  2. College of Medicine, University of South Alabama, Mobile, Alabama, USA

    Stephen W. Schaffer

  3. Department of Developmental Neurobiology, NY State Institute for Basic Research in Developmental Disabilities, New York, USA

    Eunkyue Park

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Shin, KO., Yoon, J.A., Choi, KS. (2017). The Effect on Blood Biochemical Factors of a ICR-Mice in a High-Fat Diet with Taurine 20%. In: Lee, DH., Schaffer, S.W., Park, E., Kim, H.W. (eds) Taurine 10. Advances in Experimental Medicine and Biology, vol 975. Springer, Dordrecht. https://doi.org/10.1007/978-94-024-1079-2_77

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