Abstract
Creutzfeldt-Jakob disease (CJD) is a human subacute or acute spongiform encephalopathy caused by prion protein (PrP), which is pathologically characterized by spongiform degenerations. CJD is also known as cortico-striato-spinal degeneration, subacute spongiform virus encephalopathy, or transmissible dementia. It was nominated after the name of two neuropathologists, Creutzfeldt and Jakob, who firstly reported it in 1920 and 1921, respectively. Based on the etiological factors, CJD is classified into four types: sporadic CJD (sCJD), familial CJD or genetic CJD (fCJD or gCJD), iatrogenic CJD (iCJD), and variant CJD (vCJD), with sporadic CJD (sCJD) being clinically the most common.
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© 2015 Springer Science+Business Media Dordrecht and People's Medical Publishing House
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Song, W., Zhang, R. (2015). Creutzfeldt-Jakob Disease. In: Li, H. (eds) Radiology of Infectious Diseases: Volume 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9882-2_11
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DOI: https://doi.org/10.1007/978-94-017-9882-2_11
Publisher Name: Springer, Dordrecht
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