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Explanation in Biology: An Introduction

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Explanation in Biology

Part of the book series: History, Philosophy and Theory of the Life Sciences ((HPTL,volume 11))

Abstract

Explanation in biology has long been characterized as being different from explanation in other scientific disciplines, in particular from explanation in physics. One of the reasons was the existence in biology of explanation types that were unheard of in the physical sciences: teleological and functional explanations, historical and evolutionary explanations. More recently, owing in part to the rise of molecular biology, biological explanations have been depicted as mechanisms. This profusion of explanatory patterns is typical of biology. The aim of the present volume Explanation in Biology. An Enquiry into the Diversity of Explanatory Patterns in the Life Sciences is to shed some new light on the diversity of explanation models in biology. In this introductory chapter, we recall the general philosophical context of scientific explanation as it has unfolded in the past seven decades, and highlight the specific issues that models of explanation have faced in biology. We then show how the different essays gathered in this collective volume tackle aspects of this important debate.

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References

  • Achinstein, P. (1983). The nature of explanation. New York: Oxford University Press.

    Google Scholar 

  • Ayer, A. J. (1956). What is a law of nature? Revue Internationale de Philosophie, 36, 144–165.

    Google Scholar 

  • Baetu, T. (2015). From mechanisms to mathematical models and back to mechanisms: Quantitative mechanistic explanations. In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 345–363). Dordrecht: Springer.

    Google Scholar 

  • Baker, A. (2009). Mathematical explanation in science. The British Journal for the Philosophy of Science, 60(3), 611–633. doi:10.1093/bjps/axp025.

    Google Scholar 

  • Baker, A. (2015). Mathematical explanation in biology. In P. A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 229–247). Dordrecht: Springer.

    Google Scholar 

  • Barnes, E. (1992). Explanatory unification and the problem of asymmetry. Philosophy of Science, 59, 558–571.

    Google Scholar 

  • Barros, D. B. (2008). Natural selection as a mechanism. Philosophy of Science, 75, 306–322.

    Google Scholar 

  • Baumgartner, M. (2009). Interventionist causal exclusion and non-reductive physicalism. International Studies in the Philosophy of Science, 23(2), 161–178.

    Google Scholar 

  • Beatty, J. (1995). The evolutionary contingency thesis. In G. Wolters & J. G. Lennox (Eds.), Concepts, theories, and rationality in the biological sciences, the second Pittsburgh-Konstanz colloquium in the philosophy of science (p. 1995). Pittsburgh: University of Pittsburgh Press.

    Google Scholar 

  • Bechtel, W. (2015). Generalizing mechanistic explanations using graph-theoretic representations. In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 199–225). Dordrecht: Springer.

    Google Scholar 

  • Bechtel, W., & Abrahamsen, A. (2012). Thinking dynamically about biological mechanisms: Networks of coupled oscillators. Foundations of Science, 18(4), 707–723. doi:10.1007/s10699-012-9301-z.

    Google Scholar 

  • Bechtel, W., & Richardson, R. C. (1993). Discovering complexity: Decomposition and localization as strategies in scientific research. Princeton: Princeton University Press.

    Google Scholar 

  • Bogen, J. (2005). Regularities and causality; generalizations and causal explanations. Studies in History and Philosophy of Science Part C, 36(2), 397–420.

    Google Scholar 

  • Braillard, P.-A. (2015). Prospect and limits of explaining biological systems in engineering terms. In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 319–344). Dordrecht: Springer.

    Google Scholar 

  • Brandon, R. (1997). Does biology have laws? The experimental evidence. Philosophy of Science, 64, S444–S457.

    Google Scholar 

  • Breidenmoser, T., & Wolkenhauer, O. (2015). Explanation and organizing principles in systems biology. In P. A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 249–264). Dordrecht: Springer.

    Google Scholar 

  • Brigandt, I. (2013). Explanation in biology: Reduction, pluralism, and explanatory aims. Science & Education, 22, 69–91.

    Google Scholar 

  • Brigandt, I. (2015). Evolutionary developmental biology and the limits of philosophical accounts of mechanistic explanation. In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 135–173). Dordrecht: Springer.

    Google Scholar 

  • Bromberger, S. (1966). Why questions. In R. Colodny (Ed.), Mind and cosmos: Essays in contemporary science and philosophy. Pittsburgh: University of Pittsburgh Press.

    Google Scholar 

  • Cartwright, N. (1979). Causal laws and effective strategies. Noûs, 13, 419–437.

    Google Scholar 

  • Cartwright, N. (1980). Do the laws of physics state the facts? Pacific Philosophical Quarterly, 61, 75–84.

    Google Scholar 

  • Cartwright, N. (2006). From metaphysics to method: Comments on manipulability and the causal Markov condition. The British Journal for the Philosophy of Science, 57(1), 197–218. doi:10.1093/bjps/axi156.

    Google Scholar 

  • Clayton, R. (1996). The logic of historical explanation. University Park: Pennsylvania State University Press.

    Google Scholar 

  • Craver, C. F. (2007). Explaining the brain: Mechanisms and the mosaic unity of neuroscience. Oxford: Oxford University Press.

    Google Scholar 

  • Craver, C. F., & Darden, L. (2013). In search of mechanisms: Discoveries across the life sciences. Chicago: University of Chicago Press.

    Google Scholar 

  • Cummins, R. (1975). Functional analysis. Journal of Philosophy, 72, 741–765.

    Google Scholar 

  • DesAutels, L. (2009). Sober and Elgin on laws of biology: A critique. Biology & Philosophy, 25(2), 249–256. doi:10.1007/s10539-009-9182-x.

    Google Scholar 

  • Dowe, P. (2000). Physical causation. Cambridge: Cambridge University Press.

    Google Scholar 

  • Dray, W. (1977). Les explications causales en histoire. Philosophiques, 4(1), 3–34.

    Google Scholar 

  • Dretske, F. I. (1977). Laws of nature. Philosophy of Science, 44(2), 248–268.

    Google Scholar 

  • Elgin, M. (2006). There may be strict empirical laws in biology, after all. Biology & Philosophy, 21(1), 119–134. doi:10.1007/s10539-005-3177-z.

    Google Scholar 

  • Fagan, M. B. (2015). Explanatory interdependence: The case of stem cell reprogramming. In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 387–412). Dordrecht: Springer.

    Google Scholar 

  • Franklin-Hall, L. R. (2015). Explaining causal selection with explanatory causal economy: Biology and beyond. In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 413–438). Dordrecht: Springer.

    Google Scholar 

  • Friedman, M. (1974). Explanation and scientific understanding. Journal of Philosophy, 71, 5–19.

    Google Scholar 

  • Glennan, S. S. (1996). Mechanisms and the nature of causation. Erkenntnis, 44(1), 49–71.

    Google Scholar 

  • Glennan, S. S. (2002). Rethinking mechanistic explanation. Philosophy of Science, 69(3), S342–S353.

    Google Scholar 

  • Glennan, S. (2009). Ephemeral mechanisms and historical explanation. Erkenntnis, 72(2), 251–266. doi:10.1007/s10670-009-9203-9.

    Google Scholar 

  • Glymour, B. (2008). Stable models and causal explanation in evolutionary biology. Philosophy of Science, 75(5), 571–583.

    Google Scholar 

  • Gould, S. J., & Lewontin, R. C. (1979). The spandrels of San Marco and the Panglossian paradigm: A critique of the adaptationist programme. Proceedings of the Royal Society of London B, 205, 581–598.

    Google Scholar 

  • Gross, F. (2015). The relevance of irrelevance: Explanation in systems biology. In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 175–198). Dordrecht: Springer.

    Google Scholar 

  • Haufe, C. (2013). From necessary chances to biological laws. British Journal for the Philosophy of Science, 64(2), 279–295.

    Google Scholar 

  • Hempel, C. (1965). Aspects of scientific explanation and other essays in the philosophy of science. New York: Free Press.

    Google Scholar 

  • Hempel, C., & Oppenheim, P. (1948). Studies in the logic of explanation. Philosophy of Science, 15, 135–175.

    Google Scholar 

  • Hitchcock, C. (1995). Discussion: Salmon on explanatory relevance. Philosophy of Science, 62, 304–320.

    Google Scholar 

  • Hull, D. (1974). The philosophy of biological science. Englewood Cliffs: Prentice-Hall.

    Google Scholar 

  • Hull, D. (1992). The particular circumstance model of scientific explanation. In M. H. Nitecki & D. V. Nitecki (Eds.), History and evolution. Albany: State University of New York Press.

    Google Scholar 

  • Issad, T., & Malaterre, C. (2015). Are dynamic mechanistic explanations still mechanistic? In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 265–292). Dordrecht: Springer.

    Google Scholar 

  • Kaplan, D. M., & Bechtel, W. (2011). Dynamical models: An alternative or complement to mechanistic explanations? Topics in Cognitive Science, 3(2), 438–444.

    Google Scholar 

  • Kitcher, P. (1981). Explanatory unification. Philosophy of Science, 48, 507–531.

    Google Scholar 

  • Kitcher, P. (1989). Explanatory unification and the causal structure of the world. In P. Kitcher & W. Salmon (Eds.), Scientific explanation (pp. 410–505). Minneapolis: University of Minnesota Press.

    Google Scholar 

  • Kitcher, P., & Salmon, W. (1987). Van Fraassen on explanation. The Journal of Philosophy, 84(6), 315–330.

    Google Scholar 

  • Kyburg, H. (1965). Comment. Philosophy of Science, 32, 147–151.

    Google Scholar 

  • Lange, M. (1995). Are there natural laws concerning particular species. Journal of Philosophy, 112, 430–451.

    Google Scholar 

  • Machamer, P., Darden, L., & Craver, C. (2000). Thinking about mechanisms. Philosophy of Science, 67, 1–25.

    Google Scholar 

  • Mayr, E. (1988). Towards a new philosophy of biology: Observations of an evolutionist. Cambridge: Harvard University Press.

    Google Scholar 

  • Mekios, C. (2015). Explanation in systems biology: Is it all about mechanisms? In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 47–72). Dordrecht: Springer.

    Google Scholar 

  • Merlin, F. (2015). Developmental noise: Explaining the specific heterogeneity of individual organisms. In Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 91–110). Dordrecht: Springer.

    Google Scholar 

  • Millikan, R. G. (1989). In defense of proper functions. Philosophy of Science, 56, 288–302.

    Google Scholar 

  • Mitchell, S. (1997). Pragmatic laws. Philosophy of Science, 64(4), S468–S479.

    Google Scholar 

  • Mitchell, S. (2008). Exporting causal knowledge in evolutionary and developmental biology. Philosophy of Science, 75(5), 697–706.

    Google Scholar 

  • Morange, M. (2015). Is there an explanation for… the diversity of explanations in biological sciences? In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 31–46). Dordrecht: Springer.

    Google Scholar 

  • Morrison, M. (2000). Unifying scientific theories. Cambridge: Cambridge University Press.

    Google Scholar 

  • Nagel, E. (1961). The structure of science. Problems in the logic of explanation. New York: Harcourt, Brace & World, Inc.

    Google Scholar 

  • Plutynski, A. (2004). Explanation in classical population genetics. Philosophy of Science Proceedings, 71, 1201–1215.

    Google Scholar 

  • Potochnik, A. (2007). Optimality modeling and explanatory generality. Philosophy of Science, 74(5), 680–691. doi:10.1086/525613.

    Google Scholar 

  • Press, J. (2015). Biological explanations as cursory covering law explanations. In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 367–385). Dordrecht: Springer.

    Google Scholar 

  • Reichenbach, H. (1958). The philosophy of space and time. New York: Dover Publications.

    Google Scholar 

  • Richardson, A. (1995). Explanation: Pragmatics and asymmetry. Philosophical Studies, 80(2), 109–129.

    Google Scholar 

  • Rosenberg, A. (1994). Instrumental biology or the disunity of science. Chicago: The University of Chicago Press.

    Google Scholar 

  • Ruse, M. (1970). Are there laws in biology? Australasian Journal of Philosophy, 48(2), 234–246.

    Google Scholar 

  • Salmon, W. (1965). The status of prior probabilities in statistical explanations. Philosophy of Science, 33, 137–146.

    Google Scholar 

  • Salmon, W. (1971). Statistical explanation. In W. Salmon (Ed.), Statistical explanation and statistical relevance (pp. 29–87). Pittsburgh: University of Pittsburgh Press.

    Google Scholar 

  • Salmon, W. (1978). Why ask “why?”? – an inquiry concerning scientific explanation. Proceedings and Addresses of the American Philosophical Association, 51(6), 683–705.

    Google Scholar 

  • Salmon, W. (1984). Scientific explanation and the causal structure of the world. Princeton: Princeton University Press.

    Google Scholar 

  • Salmon, W. (1989). Four decades of scientific explanation. Minneapolis: University of Minnesota Press.

    Google Scholar 

  • Salmon, W. (1994). Causality without counterfactuals. Philosophy of Science, 61, 297–312.

    Google Scholar 

  • Schaffner, K. (1993). Discovery and explanation in biology and medicine. Chicago: University of Chicago Press.

    Google Scholar 

  • Scriven, M. (1962). Explanations, predictions, and laws. In H. Feigl & G. Maxwell (Eds.), Minnesota studies in the philosophy of science, scientific explanation, space, and time (Vol. 3, pp. 170–230). Minneapolis: University of Minnesota Press.

    Google Scholar 

  • Skipper, R. A., & Millstein, R. L. (2005). Thinking about evolutionary mechanisms: Natural selection. Studies in History and Philosophy of Biological and Biomedical Sciences, 36, 327–347.

    Google Scholar 

  • Smart, J. C. C. (1962). Philosophy and scientific realism. London: Routledge and Kegan Paul.

    Google Scholar 

  • Sober, E. (1983). Equilibrium explanation. Philosophical Studies, 43(2), 201–210.

    Google Scholar 

  • Sober, E. (1993). Philosophy of biology. Boulder: Westview.

    Google Scholar 

  • Sober, E. (2003). Two uses of unification. In F. Stadler (Ed.), Institute Vienna circle yearbook 2002. Dordrecht: Kluwer.

    Google Scholar 

  • Spirtes, P., Glymour, C., & Scheines, R. (1983). Causation, prediction and search. New York: Springer.

    Google Scholar 

  • Sterelny, K. (1996). Explanatory pluralism in evolutionary biology. Biology and Philosophy, 11(2), 193–214.

    Google Scholar 

  • Strevens, M. (2008). Comments on Woodward, making things happen. Philosophy and Phenomenological Research, 77(1), 171–192.

    Google Scholar 

  • Théry, F. (2015). Explaining in contemporary molecular biology: Beyond mechanisms. In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 113–133). Dordrecht: Springer.

    Google Scholar 

  • Turner, D. (2015). Historical contingency and the explanation of evolutionary trends. In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 73–90). Dordrecht: Springer.

    Google Scholar 

  • van Fraassen, B. (1980). The scientific image. Oxford: Clarendon.

    Google Scholar 

  • Waters, C. K. (1998). Causal regularities in the biological world of contingent distributions. Biology and Philosophy, 13, 5–36.

    Google Scholar 

  • Waters, C. K. (2007). Causes that make a difference. The Journal of Philosophy, 104(11), 551–579.

    Google Scholar 

  • Weber, M. (2005). Philosophy of experimental biology. Cambridge: Cambridge University Press.

    Google Scholar 

  • Weber, M. (2008). Causes without mechanisms: Experimental regularities, physical laws, and neuroscientific explanation. Philosophy of Science, 75(5), 995–1007. doi:10.1086/594541.

    Google Scholar 

  • West, G. B., Brown, J. H., & Enquist, B. J. (1997). A general model for the origin of allometric scaling laws in biology. Science, 276(5309), 122–126.

    Google Scholar 

  • Woodward, J. (1989). The causal/mechanical model of explanation. In P. Kitcher & W. Salmon (Eds.), Scientific explanation. Minnesota studies in the philosophy of science (Vol. 13, pp. 357–383). Minneapolis: University of Minnesota Press.

    Google Scholar 

  • Woodward, J. (2000). Explanation and invariance in the special sciences. British Journal for the Philosophy of Science, 51, 197–254.

    Google Scholar 

  • Woodward, J. (2002). What is a mechanism? A counterfactual account. Philosophy of Science, 69, S366–S377.

    Google Scholar 

  • Woodward, J. (2003). Making things happen: A theory of causal explanation. Oxford: Oxford University Press.

    Google Scholar 

  • Woodward, J. (2010). Causation in biology: Stability specificity, and the choice of levels of explanation. Biology and Philosophy, 25, 287–318.

    Google Scholar 

  • Wouters, A. (2005). The function debate in philosophy. Acta Biotheoretica, 53, 123–151.

    Google Scholar 

  • Wright, L. (1973). Functions. The Philosophical Review, 82, 139–168.

    Google Scholar 

  • Zednik, C. (2015). Heuristics, descriptions, and the scope of mechanistic explanation. In P.-A. Braillard & C. Malaterre (Eds.), Explanation in biology. An enquiry into the diversity of explanatory patterns in the life sciences (pp. 295–317). Dordrecht: Springer.

    Google Scholar 

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Acknowledgements

We thank two anonymous reviewers for their comments and their suggestions of additional references. CM acknowledges support from UQAM research chair in Philosophy of science.

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  1. Independent Scholar, Peyregrand, 12350, Drulhe, France

    Pierre-Alain Braillard

  2. Département de philosophie & CIRST, Chaire de recherche UQAM en Philosophie des sciences, Université du Québec à Montréal (UQAM), Case postale 8888, Succursale Centre-Ville, Montréal, QC, H3C 3P8, Canada

    Christophe Malaterre

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Braillard, PA., Malaterre, C. (2015). Explanation in Biology: An Introduction. In: Explanation in Biology. History, Philosophy and Theory of the Life Sciences, vol 11. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9822-8_1

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