Abstract
Although the biological effect of hydrogen was first reported in 1975, it did not draw much attention. Since the protective effects of small amount of hydrogen on oxidative stress were revealed in 2007, recent years have witnessed a tremendous development of hydrogen biology. Hydrogen has been proved effective in various diseases including ischemia/reperfusion injuries, diabetes, pancreatitis, ulcerative colitis, and so on. However, the underlying mechanism is still not clear. Neutralizing toxic oxygen species only explains part of the phenomena and is now being challenged by increasingly accumulated evidence. The future direction for hydrogen biology lies in molecular mechanism, clinical study, and in other biological systems. Besides, some other small molecules like helium and methane are worth exploring.
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Chen, X., Sun, X., Ohta, S. (2015). Future Directions in Hydrogen Studies. In: Sun, X., Ohta, S., Nakao, A. (eds) Hydrogen Molecular Biology and Medicine. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9691-0_8
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DOI: https://doi.org/10.1007/978-94-017-9691-0_8
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