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Applications of Peptide Retention Time in Proteomic Data Analysis

  • Chen ShaoEmail author
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 845)

Abstract

In proteomic studies, liquid chromatography is commonly used to separate peptide mixtures prior to mass spectrometry (MS) detection. As an independent dimension of information from the information provided by the MS, peptide retention time information has been proven to be able to aid proteomic data analysis in many aspects. So far, some popular software has offered options for this information for MS data acquisition and analysis. This chapter is a brief review of current methodologies of retention time prediction and application in proteomic analysis.

Keywords

Retention time Peptide identification Quality control 

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Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  1. 1.National Key Laboratory of Medical Molecular Biology, Department of PathophysiologyInstitute of Basic Medical Sciences, Chinese Academy of Medical SciencesBeijingChina

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