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Human Urine Proteome: A Powerful Source for Clinical Research

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Urine Proteomics in Kidney Disease Biomarker Discovery

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 845))

Abstract

As noninvasive and easily available biological fluid, urine is becoming an ideal sample for proteomic study. In recent years, researchers endeavored in profiling urinary proteome and discovering potential disease biomarkers. However, there are still many challenges in the studies of urinary proteome for the complexity of urine. In this article, we review current status of urinary sample preparation, including collection, storage, and extraction of urinary proteins, and the overall urinary proteome analysis so far, which may be helpful for urinary proteome analysis.

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Authors and Affiliations

  1. Core Facility of Instrument, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Dong Dan San Tiao, Beijing, 100005, China

    Lili Zou & Wei Sun

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  1. Lili Zou
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  2. Wei Sun
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Correspondence to Wei Sun .

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  1. Pathophysiology, Peking Union Medical College & Inst. Basic Medical Sciences Chinese Academy of Medical Sciences, Beijing, China

    Youhe Gao

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Zou, L., Sun, W. (2015). Human Urine Proteome: A Powerful Source for Clinical Research. In: Gao, Y. (eds) Urine Proteomics in Kidney Disease Biomarker Discovery. Advances in Experimental Medicine and Biology, vol 845. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9523-4_4

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