Human Urine Proteome: A Powerful Source for Clinical Research

  • Lili Zou
  • Wei SunEmail author
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 845)


As noninvasive and easily available biological fluid, urine is becoming an ideal sample for proteomic study. In recent years, researchers endeavored in profiling urinary proteome and discovering potential disease biomarkers. However, there are still many challenges in the studies of urinary proteome for the complexity of urine. In this article, we review current status of urinary sample preparation, including collection, storage, and extraction of urinary proteins, and the overall urinary proteome analysis so far, which may be helpful for urinary proteome analysis.


Urinary proteome Mass spectrometry Preparation and storage Normal human 


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Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  1. 1.Core Facility of Instrument, Institute of Basic Medical SciencesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

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