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Active Constituents in Danshen and Their Pharmacological Actions

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Book cover Dan Shen (Salvia miltiorrhiza) in Medicine

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Abstract

Early in the 1930s, studies were initiated on the material basis of pharmacological activity in Danshen. Initially, major liposoluble constituents, e.g., tanshinone I, cryptotanshinone, tanshinone IIA, and tanshinone IIB, were isolated from the root of Danshen. In the 1940s, Wang Xu et al. proved that tanshinone I structurally belongs to the tetracyclic compounds of diterpene quinone. In the 1970s, a large number of studies in China were conducted on the chemistry and pharmacology of lipo- and water-soluble constituents in Danshen. In recent years, with extensive application of new techniques and improvements in the techniques of compound isolation and analysis, more and more chemical constituents have been identified from Danshen.

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Authors and Affiliations

  1. Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China

    Ailin Liu, Yitao Wang, Guanhua Du, Xiuying Yang, Juntian Zhang, Minke Tang, Ji Chen, Yonghong Chen, Zhiwei Qu, Jie Wang, Xiaoying Wang, Yan Sun, Ping Chen & Chuan Li

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  1. Ailin Liu
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Correspondence to Guanhua Du , Guanhua Du , Guanhua Du or Guanhua Du .

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  1. Tianjin, China

    Xijun Yan

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Liu, A. et al. (2015). Active Constituents in Danshen and Their Pharmacological Actions. In: Yan, X. (eds) Dan Shen (Salvia miltiorrhiza) in Medicine. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9463-3_3

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