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Campylobacter: Animal Reservoirs, Human Infections, and Options for Control

  • Jaap A. WagenaarEmail author
  • Diane G. Newell
  • Ruwani S. Kalupahana
  • Lapo Mughini-Gras
Chapter

Abstract

Campylobacteriosis is a frequently diagnosed disease in humans. Most infections are considered food-borne and are caused by Campylobacter jejuni and C. coli. The animal reservoirs of these Campylobacter, and the sources and routes of transmission, are described and discussed. Most warm-blooded animals can be colonized by Campylobacter, but avians, and in particular poultry, are preferred hosts. Much of the world’s poultry production is colonized by Campylobacter. Source attribution studies estimate that 20–40 % of cases are attributed to the handling and consumption of chicken meat, while up to 80 % of cases are due to Campylobacter found in the chicken reservoir. The difference suggests that routes other than through the food chain, i.e. environmental contamination, are important. Thus the most effective interventions would be targeted to primary production. To date, only improved biosecurity is available. If effectively implemented strict biosecurity can reduce the number of Campylobacter-positive flocks, but implementation to this level has proved difficult for the poultry industry. Available interventions in chicken processing plants can substantially reduce Campylobacter numbers on carcasses and consequently reduce the risk to humans. Public health strategies therefore utilize control programs, which aim at reducing the level of Campylobacter by measures along the food chain. It is now recognized that commercially acceptable complementary interventions for primary production, such as vaccines, bacteriophages, feed additives, are urgently needed. Once Campylobacter in poultry is controlled then other minor sources of Campylobacter including contaminated drinking water, direct contact with (pet) animals, and other food items (e.g. red meat and milk), can be addressed.

Keywords

Chicken Meat Poultry Meat Multi Locus Sequence Typing Biosecurity Measure Source Attribution 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

This work was supported in part by The Danish Council for Strategic Research (project CamVac, contract number 09-067131); by the CamCon project (Campylobacter Control—Novel Approaches in Primary Poultry Production), funded by the European Community’s Seventh Framework Programme (FP7/2007–2013) under grant agreement number 244547 (JAW). WHO Global Food-Borne Infections Network (GFN) is acknowledged for the stimulating discussions.

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© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  • Jaap A. Wagenaar
    • 1
    • 2
    • 3
    Email author
  • Diane G. Newell
    • 4
  • Ruwani S. Kalupahana
    • 5
  • Lapo Mughini-Gras
    • 1
    • 6
  1. 1.Faculty of Veterinary Medicine, Department of Infectious Diseases and ImmunologyUtrecht UniversityUtrechtThe Netherlands
  2. 2.Central Veterinary Institute of Wageningen URLelystadThe Netherlands
  3. 3.WHO Collaborating Center for Campylobacter/OIE Reference Laboratory for CampylobacteriosisLelystadThe Netherlands
  4. 4.Food-borne Zoonoses ConsultancySilver BirchesAndoverUK
  5. 5.Faculty of Veterinary Medicine and Animal Science, Department of Veterinary Public Health and PharmacologyUniversity of PeradeniyaPeradeniyaSri Lanka
  6. 6.Centre for Infectious Disease ControlNational Institute for Public Health and the Environment (RIVM)BilthovenThe Netherlands

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