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Zoonoses - Infections Affecting Humans and Animals pp 527–571Cite as

Elimination of Rabies—A Missed Opportunity

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Abstract

Rabies is one of the oldest known zoonoses. Recognized etiological agents consist of at least 15 proposed species of lyssaviruses with primary reservoirs residing in the Orders Carnivora and Chiroptera. A plethora of viral variants, maintained by a diverse set of abundant hosts, presents a formidable challenge to a strict concept of true disease eradication. Despite the availability of affordable and efficacious animal and human vaccines, today however dog rabies continues to escalate unabated across much of Asia and Africa, causing millions of suspect human exposures and tens of thousands of human rabies deaths annually. By identifying what hampers global human rabies elimination this chapter emphasizes that, given the global epidemiology of rabies, the “One Health” concept is key to solving the problem. Next to state of the art human rabies prevention, immunization and experimental therapy, it is obvious that human rabies can only be eliminated through rabies control at the animal source. This ‘paradigm shift’, however, needs new grassroot initiatives as well as political will and the closing of ranks of all stakeholders in the near future.

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Authors and Affiliations

  1. Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institute (FLI), 17493 Greifswald-Insel Riems, Germany

    Thomas Müller & Conrad M. Freuling

  2. Global Alliance for Rabies Control (GARC), Kanas, USA

    Charles E. Rupprecht, Deborah J. Briggs & Louise H. Taylor

  3. St George’s Medical School, University of London, London, UK

    Leonard Both

  4. Department of Virology, Wildlife Zoonoses and Vector-borne Diseases Research Group, Animal and Plant Health Agency, Woodham Lane, KT15 3NB, Surrey, UK

    Anthony R. Fooks

  5. Department of Clinical Infection, Microbiology and Immunology, University of Liverpool, L3 5TQ, Liverpool, UK

    Anthony R. Fooks

  6. Boyd Orr Centre for Population and Ecosystem Health Institute of Biodiversity, Animal Health and Comparative Medicine College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK

    Tiziana Lembo

  7. Global Alliance for Rabies Control (GARC), Geneva, Switzerland

    Lea Knopf

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  1. Thomas Müller
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  1. Dept. of Infectiology, Bavarian Health and Food Safety Authority, Oberschleißheim, Bayern, Germany

    Andreas Sing

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© 2015 Springer Science+Business Media Dordrecht

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Müller, T. et al. (2015). Elimination of Rabies—A Missed Opportunity. In: Sing, A. (eds) Zoonoses - Infections Affecting Humans and Animals. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9457-2_21

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