Abstract
Surface plasmon resonance (SPR) biosensors are widely used in label-free biological detections. The common SPR biosensors utilize the prism or grating coupling method to meet the momentum matching conditions. In addition to the prism or grating methods, biosensors based on periodic nanostructures take advantages of chip-based and high-throughput detections. In periodic gold nanoslits, the optical transmission is usually accompanied by an asymmetrical resonance, known as Fano resonance . It is formed due to the interference of a narrowband SPR resonance with a broadband gap resonance. In this work, several factors that can enhance the Fano resonance properties and detection limits of gold nanoslit sensors are discussed, including (1) dimension and period of the nanoslits, (2) spectral integration analysis, and (3) thermally annealed gold film. By using above methods and nanostructures, the detection sensitivity and resolution will be comparable or even higher than conventional expensive SPR system.
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- ε :
-
Dielectric constants of outside environment
- ε m :
-
Dielectric constants of metal
- n :
-
The refractive index of outside environment
- L spp :
-
Propagating length
- k spp :
-
Propagation constant of surface plasmon
- k g :
-
Grating wavevector
- E x :
-
x-component of the electric field
- E z :
-
z-component of the electric field
- θ:
-
Angle of incidence in a medium
- λ:
-
Wavelength
- λ0 :
-
Reference wavelength
- RIU :
-
Refractive index unit
- P:
-
Period
- i, j :
-
Orders of Bragg condition
- S λ :
-
Wavelength sensitivity
- S I :
-
Intensity sensitivity
- n eff :
-
Equivalent refractive index of surface plasmon
- w :
-
Width of the gold nanoslit
- h :
-
Thickness of the gold film
- ϕ :
-
Phase shift
- R :
-
Integrated response
- n 0 :
-
Reference refractive index
- λ 1,λ 2 :
-
Integrated wavelength range
- T i :
-
ith order of the resonant transmission
- δλ :
-
Wavelength resolution of the spectrometer
- Δλ :
-
Full width at half maximum (FWHM) bandwidth
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Lee, KL., Wu, SH., Wei, PK. (2015). Plasmonic Nanoslit Arrays for Sensitive Biosensors. In: Lee, CC. (eds) The Current Trends of Optics and Photonics. Topics in Applied Physics, vol 129. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9392-6_25
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