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Comparison of Microwave Ablation with Resection and with Radiofrequency Ablation Treatment in Hepatocellular Carcinoma

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Microwave Ablation Treatment of Solid Tumors

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Abstract

According to the Barcelona Clinic Liver Cancer classification and Milan criteria, the early-stage (≤5 cm, ≤3 nodules) hepatocellular carcinoma (HCC) patients are candidates for radical hepatic resection and ablation therapy. Radiofrequency ablation has obtained wide use worldwide and been deemed as the first-line technique for small HCC. As one of the most recent and exciting advances in the field of thermoablative technology, microwave ablation also achieves favorable local tumor control and survival effect with low complications in HCC therapy. However, the comparison studies of microwave ablation with resection and microwave ablation with radiofrequency ablation for HCC are relatively limited with very inconsistent results and majority of them didn’t use the newly cool-tip ablation equipment. The purpose of this chapter is to present a prospective comparative study with a large-scale sample, long-term follow-up, and newly developed ablation electrode to evaluate the clinical efficacy between resection and ablation for early-stage HCC treatment. Multiple parameters including liver function, operation time, hospitalization, cost, recurrence, survival, and complication are summarized. The therapy effect of controversial 3–5 cm tumor will also be discussed.

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Abbreviations

AASLD:

American Association for the Study of the Liver

BCLC:

Barcelona Clinic Liver Cancer

EASL:

European Association for the Study of the Liver

HCC:

Hepatocellular carcinoma

HR:

Hepatic resection

LTP:

Local tumor progression

MWA:

Microwave ablation

RFA:

Radiofrequency ablation

TE:

Technique effectiveness

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Authors and Affiliations

  1. Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China

    Jie Yu MD, Ping Liang MD & Chao-nan Chen MS

Authors
  1. Jie Yu MD
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  2. Ping Liang MD
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  3. Chao-nan Chen MS
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Corresponding author

Correspondence to Ping Liang MD .

Editor information

Editors and Affiliations

  1. The Dept. of Interventional Ultrasound, Chinese PLA General Hospital, Beijing, China

    Ping Liang

  2. The Dept. of Interventional Ultrasound, Chinese PLA General Hospital, Beijing, China

    Xiao-ling Yu

  3. The Dept. of Interventional Ultrasound, Chinese PLA General Hospital, Beijing, China

    Jie Yu

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Yu, J., Liang, P., Chen, Cn. (2015). Comparison of Microwave Ablation with Resection and with Radiofrequency Ablation Treatment in Hepatocellular Carcinoma. In: Liang, P., Yu, Xl., Yu, J. (eds) Microwave Ablation Treatment of Solid Tumors. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9315-5_16

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  • DOI: https://doi.org/10.1007/978-94-017-9315-5_16

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  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-017-9314-8

  • Online ISBN: 978-94-017-9315-5

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