Abstract
Cytokinins play an important role in the modulation of plant innate immunity. Cytokinins regulate the host defense responses either positively or negatively depending on the concentrations of cytokinins available at the infection site. Cytokinin perception and signaling involve two-component phosphorelay system. Binding of cytokinin to sensor histidine kinase (AHKs) receptors initiates a phosphotransfer cascade that culminates in the phosphorylation of response regulator proteins (ARRs) which are responsible for the regulation of cytokinin signaling system. The two types of ARR transcription activators differentially modulate the defense responses. Type-A ARRs negatively regulate cytokinin signaling, and transgenic lines overexpressing type-A ARRs display decreased defense responses, while the type-B ARR transcription factor triggers enhancement of defense responses. Pathogen-associated molecular patterns modulate the expression of both type-A and type-B ARR genes. The ARR transcription activators regulate the expression of various transcription factors belonging to MYB and AP2/ERF families, which play an important role in plant immune responses. Cytokinin homeostasis in the cytokinin signaling pathway regulates plant immune responses. Cytokinin augments PAMP-triggered immunity by enhancing callose deposition. Cytokinin may trigger the phytoalexin accumulation and confer resistance against pathogens. Cytokinins have also been shown to prime plant cells for the potentiated activation of defense-related genes. Cytokinins systemically induce resistance against pathogen infection, and this resistance is orchestrated by endogenous cytokinin and salicylic acid signaling. Cytokinins enhance resistance against pathogens via a direct induction of defense-related genes, in cooperation with SA, by modulating the NPR1/TGA3-mediated signaling. Cytokinin signaling in concert with SA signaling activates defense responses. Type-A ARRs negatively regulate SA-dependent basal immunity. Cytokinin signaling system may also function independent of SA signaling system. ABA modulates the expression of genes encoding proteins involved in cytokinin biosynthesis and degradation. Synergism and antagonism between auxin and cytokinin signaling have been reported. Auxin positively or negatively regulates the expression of the genes involved in cytokinin homeostasis. Auxin also causes repression of cytokinin responses by activating type-A ARRs, which negatively regulate cytokinin signaling.
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References
Akiyoshi DE, Regier DA, Gordon MP (1987) Cytokinin production by Agrobacterium and Pseudomonas spp. J Bacteriol 169:4242–4248
Akram A, Ongena M, Duby F, Dommes J, Thonart P (2008) Systemic resistance and lipoxygenase-related defence response induced in tomato by Pseudomonas putida strain BTP1. BMC Plant Biol 8:113
Anantharaman V, Aravind I (2001) The CHASE domain: a predicted ligand-binding module in plant cytokinin receptors and other eukaryotic and bacterial receptors. Trends Biochem Sci 26:579–582
Angra-Sharma R, Sharma DK (1999) Cytokinins in pathogenesis and disease resistance of Pyrenophora teres-barley and Drechslera maydis-maize interactions during early stages of infection. Mycopathogia 148:87–95
Aoyama T, Oka A (2003) Cytokinin signal transduction in plant cells. J Plant Res 116:221–231
Argueso CT, Ferreira FJ, Epple P, To JPC, Hutchison CE, Schaller GE, Dangl JL, Kieber JJ (2012) Two-component elements mediate interactions between cytokinin and salicylic acid in plant immunity. PLoS Genet 8(1):e1002448
Argyros R, Mathews D, Chiang Y, Palmer C, Thibault D, Etheridge N, Argyros D, Mason M, Kieber J, Schaller G (2008) Type B response regulators of Arabidopsis play key roles in cytokinin signaling and plant development. Plant Cell 20:2102–2116
Babosha AV (2009) Regulation of resistance and susceptibility in wheat-powdery mildew pathosystem with exogenous cytokinins. J Plant Physiol 166:1892–1903
Barash I, Manulis-Sasson S (2007) Virulence mechanisms and host specificity of gall-forming Pantoea agglomerans. Trends Microbiol 15:538–545
Brenner WG, Ramireddy E, Heyl A, Schmulling T (2012) Gene regulation by cytokinin in Arabidopsis. Front Plant Sci 3:8
Brugiěre N, Jiao S, Hantke S, Zinselmeier C, Roessler JA, Niu X, Jones RJ, Habben JE (2003) Cytokinin oxidase gene expression in maize is localized to the vasculature, and is induced by cytokinins, abscisic acid, and abiotic stress. Plant Physiol 132:1228–1240
Camañes G, Pastor V, Cerezo M, Garcia-Andrade J, Vicedo B, Garcia-Agustin P, Flors V (2012) A deletion in NRT2.1 attenuates Pseudomonas syringae-induced hormonal perturbation, resulting in primed plant defenses. Plant Physiol 158:1054–1066
Cao H, Glazebrook J, Clarke J, Volko S, Dong X (1997) The Arabidopsis npr1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats. Cell 88:57–63
Chern M-S, Fitzgerald H, Yadav RC, Canlas PE, Dong X, Ronald PC (2001) Evidence for a disease-resistance pathway in rice similar to the NPR1-mediated signaling pathway in Arabidopsis. Plant J 27:101–113
Choi J, Huh SU, Kojima M, Sakakibara H, Paek K-H, Hwang I (2010) The cytokinin-activated transcription factor ARR2 promotes plant immunity via TGA3/NPR1-dependent salicylic acid signaling in Arabidopsis. Dev Cell 19:284–295
Choi J, Choi D, Lee R, Ryu CM, Hwang I (2011) Cytokinins and plant immunity: old foes or new friends. Trends Plant Sci 16:388–394
Clarke SF, Burritt DJ, Guy PL (1998) Influence of plant hormones on virus replication and pathogenesis-related proteins in Phaseolus vulgaris L infected with white clover mosaic potexvirus. Physiol Mol Plant Pathol 53:195–207
Conrath U (2011) Molecular aspects of defence priming. Trends Plant Sci 16:524–531
Crespi M, Vereecke D, Temmerman W, Van Montagu M, Desomer J (1994) The fas operon of Rhodococcus fascians encodes new genes required for efficient fasciation of host plants. J Bacteriol 176:2492–2501
Cumming RC, Andon NL, Haynes PA, Park M, Fischer WH, Schubert D (2004) Protein disulfide bond formation in the cytoplasm during oxidative stress. J Biol Chem 279:21749–21758
Delaney TP, Uknes S, Vernooij B, Friedrich L, Weymann K, Negrotto D, Gaffney T, Gut-Rella M, Kessmann H, Ward E, Ryals J (1994) A central role of salicylic acid in plant disease resistance. Science 266:1247–1250
Dello Ioio R, Nakamura K, Moubayidin L, Perilli S, Taniguchi M, Morita MT, Aoyama T, Costantino P, Sabatini S (2008) A genetic framework for the control of cell division and differentiation in the root meristem. Science 322:1380–1384
Desikan R, Hancock JT, Bright J, Harrison J, Weir I, Hooley R, Neill SJ (2005) A role for ETR1 in hydrogen peroxide signaling in stomatal guard cells. Plant Physiol 137:831–834
Després C, DeLong C, Glaze S, Liu E, Fobert PR (2000) The Arabidopsis NPR1/NIM1 protein enhances the DNA binding activity of a subgroup of the TGA family of bZIP transcription factors. Plant Cell 12:279–290
Fan W, Dong X (2002) In vivo interaction between NPR1 and transcription factor TGA2 leads to salicylic acid-mediated gene activation in Arabidopsis. Plant Cell 14:1377–1389
Fayza AF, Sabrey YMM (2006) Induction of resistance in Phaseolus vulgaris against TNV by salicylic acid and kinetin. Int J Agric Biol 8:47–51
Fitzgerald HA, Canlas PE, Chern M-S, Ronald PC (2005) Alteration of TGA factor activity in rice results in enhanced tolerance to Xanthomonas oryzae pv. oryzae. Plant J 43:335–347
Frébort I, Kowalska M, Hluska T, Frébortova J, Galuszka P (2011) Evolution of cytokinin biosynthesis and degradation. J Exp Bot 62:2431–2452
Fu ZQ, Yang S, Saleh A, Wang W, Ruble J, Oka N, Mohan R, Spoel SH, Tada Y, Zheng N, Dong X (2012) NPR3 and NPR4 are receptors for the immune signal salicylic acid in plants. Nature 486:228–232
Gaille C, Kast P, Hass D (2002) Salicylate biosynthesis in Pseudomonas aeruginosa. Purification and characterization of PchB, a novel bifunctional enzyme displaying isochorismate pyruvate-lyase and chorismate mutase activities. J Biol Chem 277:21768–21775
Gaille C, Reimmann C, Haas D (2003) Isochorismate synthase (PchA), the first and rate-limiting enzyme in salicylate biosynthesis of Pseudomonas aeruginosa. J Biol Chem 278:16893–16898
Garcion C, Lohmann A, Lamodiere E, Catinot J, Buchala A, Doermann P, Métraux J-P (2008) Characterization and biological function of the ISOCHORISMATE SYNTHASE2 gene of the Arabidopsis. Plant Physiol 147:1279–1287
Grennan AK (2008) Ethylene response factors in jasmonate signaling and defense response. Plant Physiol 146:1457–1458
Großkinsky DK, Naseem M, Abdelmohsen UR, Plickert N, Engelke T, Griebel T, Zeier J, Novák O, Strnad M, Pfeifhofer H, Graaff EVD, Simon U, Roitsch T (2011) Cytokinins mediate resistance against Pseudomonas syringae in tobacco through increased antimicrobial phytoalexin synthesis independent of salicylic acid signaling. Plant Physiol 157:815–830
Haberer G, Kieber J (2002) Cytokinins. New insights into a classic phytohormone. Plant Physiol 128:354–362
Hutchison CE, Kieber JJ (2002) Cytokinin signaling in Arabidopsis. Plant Cell 14:547–559
Hwang I, Sakakibara H (2006) Cytokinin biosynthesis and perception. Physiol Plant 126:528–538
Hwang I, Sheen J (2001) Two-component circuitry in Arabidopsis cytokinin signal transduction. Nature 413:383–389
Hwang I, Chen H-C, Sheen J (2002) Two-component signal transduction pathways in Arabidopsis. Plant Physiol 129:500–515
Hwang I, Sheen J, Muller B (2012) Cytokinin signaling networks. Annu Rev Plant Biol 63:353–380
Imamura A, Hanaki N, Umeda H, Nakamura A, Suzuki T, Ueguchi C, Mizuno T (1998) Response regulators implicated in His-to-Asp phosphotransfer signaling in Arabidopsis. Proc Natl Acad Sci U S A 95:2691–2696
Inoue T, Higuchi M, Hashimoto Y, Seki M, Kobayashi M, Kato T, Tabata S, Shinozaki K, Kakimoto T (2001) Identification of CRE1 as a cytokinin receptor from Arabidopsis. Nature 409:1060–1063
Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F (2002) bZIP transcription factors in Arabidopsis. Trends Plant Sci 7:106–111
Jennifer PC, Deruére J, Maxwell BB, Morris VF, Hutchison CE, Ferreira FJ, Eric Schaller G, Kieber JJ (2007) Cytokinin regulates type-A Arabidopsis response regulator activity and protein stability via two-component phosphorelay. Plant Cell 19:3901–3914
Johnson C, Mhatre A, Arias J (2008) NPR1 preferentially binds to the DNA-inactive form of Arabidopsis TGA2. Biochim Biophys Acta 1779:583–589
Joo JH, Wang S, Chen JG, Jones AM, Fedoroff NV (2005) Different signaling and cell death roles of heterotrimeric G protein α and β subunits in the Arabidopsis oxidative stress response to ozone. Plant Cell 17:957–970
Jung HW, Tschaplinski TJ, Wang L, Glazebrook J, Greenberg JT (2009) Priming in systemic plant immunity. Science 324:89–91
Kakimoto T (2001) Identification of plant cytokinin biosynthetic enzymes as dimethylallyl diphosphate:ATP/ADP isopentenyltransferases. Plant Cell Physiol 42:677–685
Kakimoto T (2003) Perception and signal transduction of cytokinins. Annu Rev Plant Biol 54:605–627
Kazan K, Manners JM (2009) Linking development to defense: auxin in plant-pathogen interactions. Trends Plant Sci 14:373–382
Kiba T, Yamada H, Sato S, Kato T, Tabata S, Yamashino T, Mizuno T (2003) The type-A response regulator, ARR15, acts as a negative regulator in the cytokinin-mediated signal transduction in Arabidopsis thaliana. Plant Cell Physiol 44:868–874
Kiba T, Naitou T, Koizumi N, Yamashino T, Sakakibara H, Mizuno T (2005) Combinatorial microarray analysis revealing arabidopsis genes implicated in cytokinin responses through the His → Asp phosphorelay circuitry. Plant Cell Physiol 46:339–355
Kim HS, Delaney TP (2002) Overexpression of TGA5, which encodes a bZIP transcription factor that interacts with NIM1/NPR1, confers SAR-independent resistance in Arabidopsis thaliana to Peronospora parasitica. Plant J 32:151–163
Kinkema M, Fan W, Dong X (2000) Nuclear localization of NPR1 is required for activation of PR gene expression. Plant Cell 12:2339–2350
Kohler A, Schwindling S, Conrath U (2002) Benzothiadiazole-induced priming for potentiated responses to pathogen infection, wounding, and infiltration of water into leaves requires the NPR1/NIM1 gene in Arabidopsis. Plant Physiol 128:1046–1056
Kravchuk Z, Vicedo B, Flors V, Camańes G, González-Bosch C, Garcia-Agustin P (2011) Priming for JA-dependent defenses using hexanoic acid is an effective mechanism to protect Arabidopsis against B. cinerea. J Plant Physiol 186:359–366
Lee DJ, Park JY, Ku SJ, Ha YM, Kim S, Kim MD, Oh MH, Kim J (2007) Genome-wide expression of Arabidopsis response regulator (ARR7) overexpression in cytokinin response. Mol Genet Genomics 277:115–137
Luna E, Bruce TJA, Roberts MR, Flors V, Ton J (2012) Next generation systemic acquired resistance. Plant Physiol 158:844–853
Martinez-Medina A, Fernández I, Sánchez-Guzmán MJ, Jung SC, Pascual JA, Pozo MJ (2013) Deciphering the hormonal signalling network behind the systemic resistance induced by Trichoderma harzianum in tomato. Front Plant Sci 4:206
Mason MG, Mathews DE, Argyros DA, Maxwell BB, Kieber JJ, Alonso JM, Ecker JRS, Shaller GE (2005) Multiple type-B response regulators mediate cytokinin signal transduction in Arabidopsis. Plant Cell 17:3007–3018
Mathys J, De Cremer K, Timmermans P, Van Kerckhove S, Lievens B, Vanhaecke M, Cammue BP, De Coninck B (2012) Genome-wide characterization of ISR induced in Arabidopsis thaliana by Trichoderma hamatum T382 against Botrytis cinerea infection. Front Plant Sci 3:108. doi:10.3389/fpls.2012.00108
Meur G, Budatha M, Gupta AD, Prakash S, Kirti PB (2006) Differential induction of NPR1 during defense responses in Brassica juncea. Physiol Mol Plant Pathol 68:128–137
Miyawaki K, Matsumoto-Kitano M, Kakimoto T (2004) Expression of cytokinin biosynthetic isopentenyltransferase genes in Arabidopsis: tissue specificity and regulation by auxin, cytokinin, and nitrate. Plant J 37:128–138
Moreau M, Tian M, Klessig DF (2012) Salicylic acid binds NPR3 and NPR4 to regulate NPR1-dependent defense responses. Cell Res. doi:10.1038/cr 2012.100
Morris RO, Jameson PE, Laloue M, Morris JW (1991) Rapid identification of cytokinins by an immunological method. Plant Physiol 95:1156–1161
Mou Z, Fan W, Dong X (2003) Inducers of plant systemic acquired resistance regulate NPR1 function through redox changes. Cell 113:935–944
Moubayidin L, Di Mambro R, Sabatini S (2009) Cytokinin-auxin crosstalk. Trends Plant Sci 14:557–562
Mougel C, Zhulin IB (2001) CHASE: an extracellular sensing domain common to transmembrane receptors from prokaryotes, lower eukaryotes and plants. Trends Biochem Sci 26:582–584
Müller B, Sheen J (2007a) Advances in cytokinin signaling. Science 318:68–69
Müller B, Sheen J (2007b) Arabidopsis cytokinin signaling pathway. Sci STKE 2007:cm5
Müller B, Sheen J (2008) Cytokinin and auxin interaction in root stem-cell specification during early embryogenesis. Nature 453:1094–1097
Naseem M, Dandekar T (2012) The role of auxin-cytokinin antagonism in plant-pathogen interactions. PLoS Pathog 8(11):e1003026. doi:10.1371/journal ppat 1003026
Naseem M, Philippi N, Hussain A, Wangorsch G, Ahmed N, Dandekar T (2012) Integrated systems view on networking by hormones in Arabidopsis immunity reveals multiple crosstalk for cytokinin. Plant Cell 24:1793–1814
Nishiyama R, Watanabe Y, Fujita Y, Le DT, Kojima M, Werner T, Vankova R, Yamaguchi-Shinozaki K, Kakimota T, Sakakibara H, Schmülling T, Tran LS (2011) Analysis of cytokinin mutants and regulation of cytokinin metabolic genes reveals important regulatory roles of cytokinins in drought, salt and abscisic acid biosynthesis. Plant Cell 23:2169–2183
Nordström A, Tarkowski P, Tarkowska D, Norbaek R, Ǻstot C, Dolezal K, Sandberg G (2004) Auxin regulation of cytokinin biosynthesis in Arabidopsis thaliana: a factor of potential importance for auxin-cytokinin-regulated development. Proc Natl Acad Sci U S A 101:8039–8044
Pertry I, Václaviková K, Depuydt S, Galuszka P, Spichal L, Temmerman W, Stes E, Schmülling T, Kakimoto T, Van Montagu MCE, Strnad M, Holsters M, Tarkowski P, Vereecke D (2009) Identification of Rhodococcus fascians cytokinins and their modus operandi to reshape the plant. Proc Natl Acad Sci U S A 106:929–934
Pertry I, Václaviková K, Gemrotova M, Spichal L, Galuszka P, Depuydt S, Temmerman W, Stes E, De Keyser A, Riefler M, Biondi S, Novák O, Schmülling T, Strnad M, Tarkowski P, Holsters M, Vereecke D (2010) Rhodococcus fascians impacts plant development through the dynamic Fas-mediated production of a cytokinin mix. Mol Plant-Microbe Interact 23:1164–1174
Pieterse CM, van der Does D, Zamioudis C, Leon-Reyes A, van Wees SC (2012) Hormonal modulation of plant immunity. Annu Rev Cell Biol 28:489–521
Pogány M, Koehl J, Heiser I, Elstner E, Barna B (2004) Juvenility of tobacco induced by cytokinin gene introduction decreases susceptibility to Tobacco necrosis virus and confers tolerance to oxidative stress. Physiol Mol Plant Pathol 65:39–47
Rashotte AM, Carson SD, To JP, Kieber JJ (2003) Expression profiling of cytokinin action in Arabidopsis. Plant Physiol 132:1998–2011
Reusche M, Kláskova J, Thole K, Truskina J, Novák O, Janz D, Strnad M, Spichal L, Lipka V, Teichmann T (2013) Stabilization of cytokinin levels enhances Arabidopsis resistance against Verticillium longisporum. Mol Plant-Microbe Interact 26:850–860
Robert-Seilaniantz A, Grant M, Jones JDG (2011) Hormone crosstalk in plant disease and defense: more than just jasmonate-salicylate antagonism. Annu Rev Phytopathol 49:317–343
Rochon A, Boyle P, Wignes T, Fobert PR, Després C (2006) The coactivator function of Arabidopsis NPR1 requires the core of its BTB/POZ domain and the oxidation of C-terminal cysteines. Plant Cell 18:3670–3685
Sakai H, Honma T, Aoyama T, Sato S, Kato T, Tabata S, Oka A (2001) ARR1, a transcription factor for genes immediately responsive to cytokinins. Science 294:1519–1521
Sakakibara H (2006) Cytokinins: activity, biosynthesis, and translocation. Annu Rev Plant Biol 57:431–449
Sano H, Seo S, Orudgev S, Youssefian K, Ishizuka K, Ohashi Y (1994) Expression of the gene for a small GTP binding protein in transgenic tobacco elevates endogenous cytokinin levels, abnormally induces salicylic acid in response to wounding, and increases resistance to tobacco mosaic virus infection. Proc Natl Acad Sci U S A 91:10556–10560
Sano H, Seo S, Koizumi N, Niki T, Iwamura H, Ohashi Y (1996) Regulation by cytokinins of endogenous levels of jasmonic and salicylic acids in mechanically wounded tobacco plants. Plant Cell Physiol 37:762–769
Shimizu-Sato S, Tanaka M, Mori H (2009) Auxin-cytokinin interactions in the control of shoot branching. Plant Mol Biol 69:429–4435
Siemens J, Keller I, Sarx J, Kunz S, Schuller A, Nagel W, Schmülling T, Parniske M, Ludwig-Müller J (2006) Transcriptome analysis of Arabidopsis clubroots indicate a key role for cytokinins in disease development. Mol Plant Microbe Interact 19:480–494
Slaughter A, Daniel X, Flors V, Luna E, Hohn B, Mauch-Mani B (2012) Descendants of primed Arabidopsis plants exhibit resistance to biotic stress. Plant Physiol 158:835–843
Spoel SH, Dong X (2012) How do plants achieve immunity? Defence without specialized immune cells. Nat Rev Immunol 12:89–100
Stepanova AN, Alonso JM (2011) Bypassing transcription: a shortcut in cytokinin-auxin interactions. Dev Cell 4:606–610
Sun F, Liu P, Xu J, Dong H (2010) Mutation in RAP2.6L, a transactivator of the ERF transcription factor family, enhances Arabidopsis resistance to Pseudomonas syringae. Physiol Mol Plant Pathol 74:295–302
Suzuki T, Miwa K, Ishikawa K, Yamada H, Aiba H, Mizuno T (2001) The Arabidopsis sensor kinase, AHK4, can respond to cytokinin. Plant Cell Physiol 42:107–113
Sziráki I, Balázs E, Király Z (1980) Role of different stresses in inducing systemic acquired resistance to TMV and increasing cytokinin level in tobacco. Physiol Plant Pathol 16:277–280
Tada Y, Spoel SH, Pajerowska-Mukhtar K, Mou Z, Song J, Dong X (2008) Plant immunity requires conformational changes of NPR1 via S-nitrosylation and thioredoxin. Science 321:952–956
Takei K, Sakakibara H, Sugiyama T (2001) Identification of genes encoding adenylate isopentenyltransferase, a cytokinin biosynthesis enzyme, in Arabidopsis thaliana. J Biol Chem 276:26405–26410
Takei K, Ueda N, Aoki K, Kuromori T, Hirayama T, Shinozaki K, Yamaya T, Sakakibara H (2004a) AtIPT3, an Arabidopsis isopentenyltransferase gene, is a key determinant of macronutrient-responsive cytokinin biosynthesis. Plant Cell Physiol 45:1053–1062
Takei K, Yamaya T, Sakakibara H (2004b) Arabidopsis CYP735A1 and CYP735A2 encode cytokinin hydroxylases that catalyze the biosynthesis of trans-zeatin. J Biol Chem 279:41866–41872
Tanaka M, Takei K, Kojima M, Sakakibara H, Mori H (2006) Auxin controls local cytokinin biosynthesis in the nodal stem in apical dominance. Plant J 45:1028–1036
Thilmony R, Underwood W, He SY (2006) Genome-wide transcriptional analysis of the Arabidopsis thaliana interaction with the plant pathogen Pseudomonas syringae pv tomato DC3000 and the human pathogen Escheria coli 0157:H7. Plant J 46:34–53
To JP, Haberer G, Ferreira FJ, Deruere J, Mason MG, Schaller GE, Alonso JM, Ecker JR, Kieber JJ (2004) Type-A Arabidopsis response regulators are partially redundant negative regulators of cytokinin signaling. Plant Cell 16:658–671
Tsai YC, Weir NR, Hill K, Zhang W, Kim HJ, Shiu S-H, Schaller GE, Kieber JJ (2012) Characterization of genes involved in cytokinin signaling and metabolism from rice. Plant Physiol 158:1666–1684
Van der Ent S, Verhagen BWM, Van Doorn R, Bakker D, Verlaan MG, Pel MJC, Joosten RG, Proveniers MCG, Van Loon LC, Ton J, Pieterse CMJ (2008) MYB72 is required in early signaling steps of rhizobacteria-induced systemic resistance in Arabidopsis. Plant Physiol 146:1293–1304
Walters DR, McRoberts N, Fitt BD (2008) Are green islands red herrings? Significance of green islands in plant interactions with pathogens and pests. Biol Rev Camb Philos Soc 83:79–102
Wang J, Ma X-M, Kojima M, Sakakibara H, Hou B-K (2011) N-Glucosyltransferase UGT76C2 is involved in cytokinin homeostasis and cytokinin response in Arabidopsis thaliana. Plant Cell Physiol 52:2200–2213
Whenham RJ (1989) Effect of systemic tobacco mosaic virus infection on endogenous cytokinin concentration in tobacco (Nicotiana tabacum L.) leaves: consequences for the control of resistance and symptom development. Physiol Mol Plant Pathol 35:85–95
Wildermuth MC, Dewdney J, Wu G, Ausubel FM (2001) Isochorismate synthesis is required to synthesize salicylic acid for plant defense. Nature 414:562–565
Wu Y, Zhang D, Chu JY, Boyle P, Wang Y, Brindle ID, De Luca V, Desprès C (2012) The Arabidopsis NPR1 protein is a receptor to the plant defense hormone salicylic acid. Cell Rep 1:639–647
Yamada H, Suzuki T, Terada K, Takei K, Ishikawa K, Miwa K, Mizyuno T (2001) The Arabidopsis AHK4 histidine kinase is a cytokinin-binding receptor that transduces cytokinin signals across the membrane. Plant Cell Physiol 42:1017–1023
Zhao Z, Andersen SU, Ljung K, Dolezal K, Miotk A, Schultheiss SJ, Lohmann JU (2010) Hormonal control of the shoot stem-cell niche. Nature 465:1089–1092
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Vidhyasekaran, P. (2015). Cytokinin Signaling System in Plant Immunity. In: Plant Hormone Signaling Systems in Plant Innate Immunity. Signaling and Communication in Plants, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9285-1_7
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