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Production of Caffeic Acid Derivatives from Adventitious Root Cultures of Echinacea purpurea (L.) Moench

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Production of Biomass and Bioactive Compounds Using Bioreactor Technology

Abstract

Echinacea purpurea (L.) Moench, the purple cone flower is one of the world’s most important medicinal herbs and active ingredients of purple cone flower are caffeic acid derivatives namely caftaric acid, chlorogenic acid, caffeic acid, cynarin, echinacoside and cichoric acid. Efforts have been made in the recent past for the production of caffeic acid derivatives from adventitious root cultures. Bioreactor cultures have been established for large-scale production of biomass and bioactive compounds and various physiological parameters affecting the biomass and accumulation of caffeic acid derivatives have been investigated. Advances in adventitious root cultures of Echinacea purpurea for the production of bioactive compounds have been summarized in this review.

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Abbreviations

DW:

Dry weight

FW:

Fresh weight

IBA:

Indole-3-butyric acid

MS medium:

Murashige and Skoog medium

SNP:

Sodium nitroprusside

vvm:

Air volume per medium volume per minute

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Acknowledgement

This study was supported by a grant of Korea Healthcare Technology R&D project, Ministry of Health and Welfare, Republic of Korea (Grant No. A103017). Dr. H. N. Murthy is thankful to Ministry of Education, Science and Technology, Republic of Korea for the award of Brain pool Fellowship (131S-4-3-0523) and this paper was studied with the support of Ministry of Science, ICT and Planning (MSIP).

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Authors and Affiliations

  1. Research Centre for the Development of Advanced Horticultural Technology, Chungbuk National University, Cheongju, 361-763, Republic of Korea

    Hosakatte Niranjana Murthy & Kee-Yoeup Paek

  2. Department of Botany, Karnatak University, Dharwad, 580003, India

    Hosakatte Niranjana Murthy

  3. Dalian Academy of Agricultural Sciences, Yingchengzi, Ganjingzi District, Dalian City, 116036, Liaoning Province, China

    Chun-Hua Wu

  4. School of Agriculture and Food Science, Zhejiang Agriculture and Forestry University, Linan, Hangzjpi, 311300, Zhejiang, China

    Yong-Yi Cui

Authors
  1. Hosakatte Niranjana Murthy
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  2. Chun-Hua Wu
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  3. Yong-Yi Cui
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  4. Kee-Yoeup Paek
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Corresponding author

Correspondence to Chun-Hua Wu .

Editor information

Editors and Affiliations

  1. Department of Horticultural Science, Chungbuk National University, Cheongju, Korea, Republic of (South Korea)

    Kee-Yoeup Paek

  2. Department of Botany, Karnatak University, Dharwad, India

    Hosakatte Niranjana Murthy

  3. School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

    Jian-Jiang Zhong

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Murthy, H.N., Wu, CH., Cui, YY., Paek, KY. (2014). Production of Caffeic Acid Derivatives from Adventitious Root Cultures of Echinacea purpurea (L.) Moench. In: Paek, KY., Murthy, H., Zhong, JJ. (eds) Production of Biomass and Bioactive Compounds Using Bioreactor Technology. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9223-3_8

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