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Production of Bioactive Compounds from Somatic Embryo Suspension Cultures of Siberian Ginseng in Bioreactors

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Production of Biomass and Bioactive Compounds Using Bioreactor Technology

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Abstract

Eleutherococcus senticosus (Rupr. & Maxim.) Maxim (Acanthopanax senticosus), popularly known as ‘Siberian ginseng’, is a woody medicinal plant which is used in traditional medicine as an adaptogen. It is marketed throughout the world as a health supplement. The major active ingredients are lignan glycosides called eleutherosides. Efforts have been made recently to produce bioactive compounds from suspension cultures of somatic embryos. Bioreactor cultures have been established for the production of embryogenic biomass and bioactive compounds. In this review, we have presented bioreactor scale production of bioactive compounds and explained various bioprocess strategies for the production of eleutheroside B, E, E1 and chlorogenic acid.

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Abbreviations

2 4-D:

2, 4-Dichlorophenoxy acetic acid

C2H4 :

Ethylene

CO2 :

Carbon dioxide

DW:

Dry weight

FW:

Fresh weight

GA3 :

Gibberellic acid

MJ:

Methyl jasmonate

MS medium:

Murashige and Skoog medium

O2 :

Oxygen

vvm:

Air volume per medium volume per minute

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Author information

Authors and Affiliations

  1. Department of Biotechnology and Genetic Engineering, Jahangirnagar University, Savar, Dhaka, 1342, Bangladesh

    Abdullah Mohammad Shohael

  2. Department of Biotechnology and Genetic Engineering, Jahangirnagar University, Dhaka, Bangladesh

    Sayeda Mahfuja Khatun

  3. Department of Botany, Karnatak University, 580 003, Dharwad, India

    Hosakatte Niranjana Murthy

  4. Research Center for the Development of Advance Horticultural Technology, Chungbuk National University, 361-763, Cheongju, Republic of Korea

    Hosakatte Niranjana Murthy & Kee-Yoeup Paek

Authors
  1. Abdullah Mohammad Shohael
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  2. Sayeda Mahfuja Khatun
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  3. Hosakatte Niranjana Murthy
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  4. Kee-Yoeup Paek
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Corresponding author

Correspondence to Abdullah Mohammad Shohael .

Editor information

Editors and Affiliations

  1. Department of Horticultural Science, Chungbuk National University, Cheongju, Korea, Republic of (South Korea)

    Kee-Yoeup Paek

  2. Department of Botany, Karnatak University, Dharwad, India

    Hosakatte Niranjana Murthy

  3. School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, China

    Jian-Jiang Zhong

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Shohael, A.M., Khatun, S.M., Murthy, H.N., Paek, KY. (2014). Production of Bioactive Compounds from Somatic Embryo Suspension Cultures of Siberian Ginseng in Bioreactors. In: Paek, KY., Murthy, H., Zhong, JJ. (eds) Production of Biomass and Bioactive Compounds Using Bioreactor Technology. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9223-3_13

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