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Genomics and Proteomics for Clinical Discovery and Development pp 7–18Cite as

Identification of Missing Proteins: Toward the Completion of Human Proteome

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Part of the book series: Translational Bioinformatics ((TRBIO,volume 6))

Abstract

Undoubtedly, one of the greatest achievements of scientific research was the completion of sequencing the human genome in 2003 that is still unmatched in size of collaborative efforts (International Human Genome Sequencing Consortium 2004). The social benefit of the knowledge generated is better understanding the expressions of genes in healthy and diseased conditions, which in turn can lead to better diagnosis and treatment of many diseases, including various forms of cancer. Notably, the technological developments have continuously delivered efficient tools to overcome the difficulties of mapping about three billion base pair long genetic codes. As an additional outcome, today, we know that the human chromosomes hold about 20,300 genes coding for all functional proteins in the wide versatility of biological activities of cells.

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Author information

Authors and Affiliations

  1. Clinical Protein Science & Imaging, Department of Biomedical Engineering, Lund University, Biomedical Center D13, SE-211 84, Lund, Sweden

    Ákos Végvári Ph.D.

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  1. Ákos Végvári Ph.D.
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Correspondence to Ákos Végvári Ph.D. .

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Editors and Affiliations

  1. Clinical Protein Science & Imaging, Biomedical Center, Biomedical Engineering, Biomedical Center D13, Lund University, Lund, Sweden

    György Marko-Varga

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Végvári, Á. (2014). Identification of Missing Proteins: Toward the Completion of Human Proteome. In: Marko-Varga, G. (eds) Genomics and Proteomics for Clinical Discovery and Development. Translational Bioinformatics, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9202-8_2

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