Molecular Mechanism of Hepatic Metastasis of Colorectal Cancer

  • Shu ZhengEmail author


In the event of distant metastasis of colorectal cancer event, the liver is the main metastatic site, accounting for about 38–60 % [1]. Early-stage hepatic metastasis of colorectal cancer has few clinical manifestations. Only 20 % of patients are suitable for surgical treatment [2], and 5-year survival rate of the patients with hepatic metastasis of colorectal cancer is nearly zero if they do not receive any treatment. Hepatic metastasis is one of the main reasons for the death of colorectal cancer patients. It is a problem that should be solved to probe the mechanism of hepatic metastasis of colorectal cancer and find molecular markers for early diagnosis and treatment targets.


Colorectal Cancer Hepatic Metastasis Vascular Endothelial Growth Factor Receptor Colorectal Cancer Cell Metastatic Focus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media Dordrecht and People's Medical Publishing House 2017

Authors and Affiliations

  1. 1.Cancer InstituteThe Second Affiliated Hospital, Zhejiang University School of MedicineHangzhouChina

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