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Cerium Dioxide CeO2-x and Orthovanadate (Gd0.9Eu0.1VO4) Nanoparticles for Protection of Living Body from X-Ray Induced Damage

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Nanomaterials for Security

Abstract

The effectiveness of CeO2−x and GdEuVO4 nanoparticles in radioprotection in model animals during radiation exposure has been shown. Nanoparticles were injected per os by two different schemes – once and during 15 days. For the 15-days scheme of GdEuVO4 nanoparticles injection during 30 days of observation the survival of animals irradiated with a dose of 6.0 Gy was 100 %; for ceria it was 90 % for ceria. It was revealed that 7.0 Gy radiation dose is lethal. These results can serve as a motivation to consider inorganic nanoparticles as the basis for new drugs possessing by radioprotective effect.

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Correspondence to G. Grygorova .

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Grygorova, G., Klochkov, V., Mamotyuk, Y., Malyukin, Y. (2016). Cerium Dioxide CeO2-x and Orthovanadate (Gd0.9Eu0.1VO4) Nanoparticles for Protection of Living Body from X-Ray Induced Damage. In: Bonča, J., Kruchinin, S. (eds) Nanomaterials for Security. NATO Science for Peace and Security Series A: Chemistry and Biology. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-7593-9_23

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