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Cancer Gene Pathways

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Abstract

The previous chapters have described what cancer genes are and how they are acquired. But what do cancer genes do? How does the inactivation of tumor suppressor genes and activation of proto-oncogenes cause proliferating cells to evolve into cancers? The answer to this question has been revealed by the functional analysis of the proteins encoded by cancer genes and their wild type counterparts.

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Bunz, F. (2016). Cancer Gene Pathways. In: Principles of Cancer Genetics. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-7484-0_6

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