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Stem Cells and Hematopoietic Cell Engineering

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Stem Cells: Basics and Clinical Translation

Part of the book series: Translational Medicine Research ((TRAMERE,volume 1))

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Abstract

Hematopoietic stem cells (HSCs) and progenitor cells possess the potential to develop all type of blood cells in the circulatory system. The generation of these blood cells as well as HSCs/HPCs ex vivo might meet the deficiency in blood cell transfusion and blaze new trails in immunotherapy, hematological disease treatment, and cancer therapy. In this chapter, the potential clinical application of hematopoietic cell‒engineering products is summarized. The obstacles, current strategies, and progress in hematopoietic cell engineering are discussed as well.

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  1. Stem Cell and Regenerative Medicine Lab, Beijing Institute of Transfusion Medicine, Beijing, 100850, China

    Xiaoyan Xie, Yanhua Li, Yanxun Sun, Jin Zhang, Fang Fang, Wen Yue & Xuetao Pei

  2. South China Research Center for Stem Cell and Regenerative Medicine, AMMS, Guangzhou, 510005, China

    Xiaoyan Xie, Yanhua Li, Yanxun Sun, Jin Zhang, Fang Fang, Wen Yue & Xuetao Pei

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Xie, X. et al. (2015). Stem Cells and Hematopoietic Cell Engineering. In: Zhao, R. (eds) Stem Cells: Basics and Clinical Translation. Translational Medicine Research, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-7273-0_5

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