Abstract
Radiofrequency ablation (RFA) to treat primary and secondary hepatic malignancies have gained widespread acceptance over the past 10 years. RFA of hepatic tumors can now be performed with low morbidity and mortality rates. Clinicians performing RFA must recognize early and late complications of RFA so as to intervene with appropriate treatment early.
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References
Dan JQ, Zhang YJ, Huang JT, Chen MS, Gao HJ, Peng ZW, Xu L, Lau WY. Hepatitis B virus reactivation after radiofrequency ablation or hepatic resection for HBV-related small hepatocellular carcinoma: a retrospective study. Eur J Surg Oncol. 2013;39(8):865–72.
Xia F, Lai EC, Lau WY, Ma K, Li X, Bie P, Qian C. High serum hyaluronic acid and HBV viral load are main prognostic factors of local recurrence after complete radiofrequency ablation of hepatitis B-related small hepatocellular carcinoma. Ann Surg Oncol. 2012;19(4):1284–91.
Curley SA, Izzo F, Ellis LM, Nicolas Vauthey J, Vallone P. Radiofrequency ablation of hepatocellular cancer in 110 patients with cirrhosis. Ann Surg. 2000;232(3):381–91.
Mulier S, Mulier P, Ni Y, Miao Y, Dupas B, Marchal G, De Wever I, Michel L. Complications of radiofrequency coagulation of liver tumours. Br J Surg. 2002;89(10):1206–22.
Rhim H, Yoon KH, Lee JM, Cho Y, Cho JS, Kim SH, Lee WJ, Lim HK, Nam GJ, Han SS, Kim YH, Park CM, Kim PN, Byun JY. Major complications after radio-frequency thermal ablation of hepatic tumors: spectrum of imaging findings. Radiographics. 2003;23(1):123–34.
Chen MH, Yan K, Yang W, Gao W, Dai Y, Wang YB, Zhang H, Huo L, Xing BC, Huang XF. Efficacy of radiofrequency ablation of 343 patients with hepatic tumor and the relevant complications. Beijing Da Xue Xue Bao. 2005;37(3):292–6.
Poggi G, Riccardi A, Quaretti P, Teragni C, Delmonte A, Amatu A, Saini G, Mazzucco M, Bernardo A, Palumbo R, Canto A, Bernieri S, Bernardo G. Complications of percutaneous radiofrequency thermal ablation of primary and secondary lesions of the liver. Anticancer Res. 2007;27(4C):2911–6.
Kasugai H, Osaki Y, Oka H, Kudo M, Seki T, Osaka Liver Cancer Study Group. Severe complications of radiofrequency ablation therapy for hepatocellular carcinoma: an analysis of 3,891 ablations in 2,614 patients. Oncology. 2007;72 Suppl 1:72–5.
Koda M, Murawaki Y, Hirooka Y, Kitamoto M, Ono M, Sakaeda H, Joko K, Sato S, Tamaki K, Yamasaki T, Shibata H, Shimoe T, Matsuda T, Toshikuni N, Fujioka S, Ohmoto K, Nakamura S, Kariyama K, Aikata H, Kobayashi Y, Tsutsui A. Complications of radiofrequency ablation for hepatocellular carcinoma in a multicenter study: an analysis of 16346 treated nodules in 13283 patients. Hepatol Res. 2012;42(11):1058–64.
Takaki H, Yamakado K, Nakatsuka A, Yamada T, Shiraki K, Takei Y, Takeda K. Frequency of and risk factors for complications after liver radiofrequency ablation under CT fluoroscopic guidance in 1500 sessions: single-center experience. AJR Am J Roentgenol. 2013;200(3):658–64.
de Baère T, Risse O, Kuoch V, Dromain C, Sengel C, Smayra T, Gamal El Din M, Letoublon C, Elias D. Adverse events during radiofrequency treatment of 582 hepatic tumors. AJR Am J Roentgenol. 2003;181(3):695–700.
Dodd 3rd GD, Napier D, Schoolfield JD, Hubbard L. Percutaneous radiofrequency ablation of hepatic tumors: postablation syndrome. AJR Am J Roentgenol. 2005;185:51–7.
Carrafiello G, Laganà D, Ianniello A, Dionigi G, Novario R, Recaldini C, Mangini M, Cuffari S, Fugazzola C. Post-radiofrequency ablation syndrome after percutaneous radiofrequency of abdominal tumours: one centre experience and review of published works. Australas Radiol. 2007;51(6):550–4.
Goto E, Tateishi R, Shiina S, Masuzaki R, Enooku K, Sato T, Ohki T, Kondo Y, Goto T, Yoshida H, Omata M. Hemorrhagic complications of percutaneous radiofrequency ablation for liver tumors. J Clin Gastroenterol. 2010;44(5):374–80.
Chen MH, Dai Y, Yan K, Yang W, Gao W, Wu W, Liao SR, Hao CY. Intraperitoneal hemorrhage during and after percutaneous radiofrequency ablation of hepatic tumors: reasons and management. Chin Med J (Engl). 2005;118(20):1682–7.
Minami Y, Hayaishi S, Kudo M. Radiofrequency ablation for hepatic malignancies: is needle tract cauterization necessary for preventing iatrogenic bleeding? Dig Dis. 2013;31(5–6):480–4.
Birsen O, Aliyev S, Aksoy E, Taskin HE, Akyuz M, Karabulut K, Siperstein A, Berber E. A critical analysis of postoperative morbidity and mortality after laparoscopic radiofrequency ablation of liver tumors. Ann Surg Oncol. 2014;21(6):1834–40.
Ohnishi T, Yasuda I, Nishigaki Y, Hayashi H, Otsuji K, Mukai T, Enya M, Omar S, Soehendra N, Tomita E, Moriwaki H. Intraductal chilled saline perfusion to prevent bile duct injury during percutaneous radiofrequency ablation for hepatocellular carcinoma. J Gastroenterol Hepatol. 2008;23(8 Pt 2):e410–5.
Nakata Y, Haji S, Ishikawa H, Yasuda T, Nakai T, Takeyama Y, Shiozaki H. Two cases of hepatocellular carcinoma located adjacent to the Glisson’s capsule treated by laparoscopic radiofrequency ablation with intraductal chilled saline perfusion through an endoscopic nasobiliary drainage tube. Surg Laparosc Endosc Percutan Tech. 2010;20(6):e189–92.
Kurihara N, Kato H, Hirao K, Mizuno O, Ishida E, Okada H, Yamamoto K. Prevention of biliary complication in radiofrequency ablation for hepatocellular carcinoma-Cooling effect by endoscopic nasobiliary drainage tube. Eur J Radiol. 2010;73:385–90.
Hirooka M, Kisaka Y, Uehara T, Ishida K, Kumagi T, Watanabe Y, Abe M, Matsuura B, Hiasa Y, Onji M. Efficacy of laparoscopic radiofrequency ablation for hepatocellular carcinoma compared to percutaneous radiofrequency ablation with artificial ascites. Dig Endosc. 2009;21(2):82–6.
Kim JS, Kim HS, Myung DS, Lee GH, Park KJ, Cho SB, Joo YE, Choi SK. A case of diaphragmatic hernia induced by radiofrequency ablation for hepatocellular carcinoma. Korean J Gastroenterol. 2013;62(3):174–8.
Nakamura T, Masuda K, Thethi RS, Sako H, Yoh T, Nakao T, Yoshimura N. Successful surgical rescue of delayed onset diaphragmatic hernia following radiofrequency ablation for hepatocellular carcinoma. Ulus Travma Acil Cerrahi Derg. 2014;20(4):295–9.
Han Y, Yu L, Hao YZ, Yang M, Liu S, Deng YB, He LF, Cai JQ, Chen MH. Percutaneous radiofrequency ablation with artificial hydrothorax for liver cancer in the hepatic dome. Zhonghua Zhong Liu Za Zhi. 2012;34(11):846–9.
Llovet JM, Vilana R, Brú C, Bianchi L, Salmeron JM, Boix L, Ganau S, Sala M, Pagès M, Ayuso C, Solé M, Rodés J, Bruix J, Barcelona ClÃnic Liver Cancer (BCLC) Group. Increased risk of tumor seeding after percutaneous radiofrequency ablation for single hepatocellular carcinoma. Hepatology. 2001;33(5):1124–9.
Jaskolka JD, Asch MR, Kachura JR, Ho CS, Ossip M, Wong F, Sherman M, Grant DR, Greig PD, Gallinger S. Needle tract seeding after radiofrequency ablation of hepatic tumors. J Vasc Interv Radiol. 2005;16(4):485–91.
Livraghi T, Lazzaroni S, Meloni F, Solbiati L. Risk of tumour seeding after percutaneous radiofrequency ablation for hepatocellular carcinoma. Br J Surg. 2005;92:856–8.
Perkins JD. Seeding risk following percutaneous approach to hepatocellular carcinoma. Liver Transpl. 2007;13(11):1603.
Imamura J, Tateishi R, Shiina S, Goto E, Sato T, Ohki T, Masuzaki R, Goto T, Yoshida H, Kanai F, Hamamura K, Obi S, Yoshida H, Omata M. Neoplastic seeding after radiofrequency ablation for hepatocellular carcinoma. Am J Gastroenterol. 2008;103:3057–62.
Latteri F, Sandonato L, Di Marco V, Parisi P, Cabibbo G, Lombardo G, Galia M, Midiri M, Latteri MA, Craxì A. Seeding after radiofrequency ablation of hepatocellular carcinoma in patients with cirrhosis: a prospective study. Dig Liver Dis. 2008;40(8):684–9.
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Lau, W.Y., Lai, E.C.H., Lau, S.H.Y. (2016). Peri-RFA Care and Management of Complications. In: Chen, M., Zhang, Y., Lau, W. (eds) Radiofrequency Ablation for Small Hepatocellular Carcinoma. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-7258-7_7
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DOI: https://doi.org/10.1007/978-94-017-7258-7_7
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