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Current Trends in Memory Implantation and Rehabilitation

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Recent Progress in Brain and Cognitive Engineering

Part of the book series: Trends in Augmentation of Human Performance ((TAHP,volume 5))

Abstract

Hippocampus is believed to be the brain region critical for memory storage and recall. Damage to the hippocampus by lesions or neurodegenerative diseases such as Alzheimer’s disease could lead to memory deficits. However, there is yet no treatment method available. Direct deep-brain stimulation (DBS) of the hippocampus has been attempted in an effort to find a treatment method for memory dysfunction and Alzheimer’s disease in the last few decades but with limited success. Recently, a novel approach has been developed where an implantation of a very large scale integration (VLSI) microchip containing a biomimetic computational model could act as an artificial bridge to replace the damaged hippocampal circuit in vivo. Here, we discuss the memory implantation techniques; from the conventional DBS method to the current memory implantation technology using an artificial neural microchip. Furthermore, we propose future directions towards the development of a physiologically realistic memory implantation chip design that could enhance the performance of the memory implant and be used for the treatment of memory-related neurodegenerative diseases.

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Authors and Affiliations

  1. Department of Brain and Cognitive Engineering, Korea University, Seoul, Republic of Korea

    Hyun Jae Jang, Sahn Woo Park & Jeehyun Kwag

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  1. Hyun Jae Jang
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  2. Sahn Woo Park
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  3. Jeehyun Kwag
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Correspondence to Jeehyun Kwag .

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Editors and Affiliations

  1. Department of Brain and Cognitive Engineering, Korea University, Seoul, Korea (Republic of)

    Seong-Whan Lee

  2. Department Human Perception, Cognition and Action, Max Planck Institute for Biological Cybernetics, Tübingen, Germany

    Heinrich H. Bülthoff

  3. Machine Learning Group, Berlin Institute of Technology, Berlin, Germany

    Klaus-Robert Müller

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Jang, H.J., Park, S.W., Kwag, J. (2015). Current Trends in Memory Implantation and Rehabilitation. In: Lee, SW., Bülthoff, H., Müller, KR. (eds) Recent Progress in Brain and Cognitive Engineering. Trends in Augmentation of Human Performance, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-7239-6_5

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