Abstract
Recently it has been reported that motilin increases lower oesophageal sphincter (LES) pressure1,2, but the physiological significance of its effect on the LES has not been elucidated. A perfused catheter method has generally been used to measure LES pressure; however, this method is not suitable for long-term measurement on conscious animals. To accomplish this, we have studied LES motor activity using force transducers chronically implanted on the serosal surface of the canine LES3. The present study was designed to determine the effect of motilin on the LES in the light of physiological changes in motor activity, both of the LES and stomach.
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References
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Aizawa, I., Hiwatashi, K., Takahashi, I., Itoh, Z. (1978). Control of motor activity in the lower oesophageal sphincter by motilin. In: Duthie, H.L. (eds) Gastrointestinal Motility in Health and Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-4389-1_12
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DOI: https://doi.org/10.1007/978-94-017-4389-1_12
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-017-4391-4
Online ISBN: 978-94-017-4389-1
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