Abstract
The interdigestive or migrating motor complex (MMC) occurs in most animal species that have been studied thus far. Little is known about the occurrence of an MMC-like phenomenon in man; and its characteristics, function, control and disorders in man have not been studied. It has been suggested that motilin plays an important part in the control of interdigestive motor activity in dogs1. The data on the mechanism of release and on the effect of meals on the serum motilin levels in man do not agree with observations in dogs2,3. The purposes of our investigations, therefore, were: (1) to study the MMC in normal subjects and patients with various gastrointestinal disorders; (2) to test the hypothesis that the absence of activity front leads to bacterial overgrowth in the small intestine; (3) to study the role of motilin in the control of human interdigestive motor activity.
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References
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Vantrappen, G., Janssens, J., Hellemans, J., Christofides, N., Bloom, S. (1978). Studies on the interdigestive (migrating) motor complex in man. In: Duthie, H.L. (eds) Gastrointestinal Motility in Health and Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-4389-1_1
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DOI: https://doi.org/10.1007/978-94-017-4389-1_1
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-017-4391-4
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