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Abstract

Small to medium sized, elongated, flat, delicate distomes with translucent tegument. Suckers weekly developed, and closely proximated. Oesophagus and pharynx present, intestinal caeca simple, may or may not reach posterior extremity. Genital pore median, just anterior to ventral sucker. Seminal vesicle tubular, coiled, cirrus sac absent. Testes usually in posterior body, diagonal or tandem, lobed or branched. Ovary pre-testicular, rarely post-testicular. Vitelline glands follicular, usually in lateral field, generally anterior to level of ovary. Uterus with numerous folds, mainly confined between ovary and genital pore, filled with numerous small and embryonated eggs. Excretory bladder with a long stem and short lateral branches.

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Further reading

  • Adam, R., Hinz, E., Sithithaworn, P., Pipitgool, V. & Storch, V. 1993. Ultrastructural hepatic alterations in hamsters and jirds after experimental infection with the liver fluke Opisthorchis viverrini. Parasitology Research, 79: 357–364.

    Article  CAS  Google Scholar 

  • Akai,P.S., Pungpak, S., Chaicumpa, W., Kitikoon, V., Ruangkunaporn, Y., Bunnag, D. & Befus, A.D. 1995. Serum antibody responses in opisthorchiasis. International Journal for Parasitology, 25: 971–973.

    Article  Google Scholar 

  • Akai, P.S., Pungpak, S., Chaicumpa, W., Viroj, K., Bunnag, D. & Befus, A.D. 1994. Serum antibody response to Opisthorchis viverrini antigen as a marker for opisthorchiasis-associated cholangiocarcinoma. Transactions of the Royal Society of Tropical Medicine and Hygiene, 88: 471–474.

    Article  PubMed  CAS  Google Scholar 

  • Akai, P.S., Pungpak, S., Kitikoon, V., Bunnag, D. & Befus, A.D. 1994. Possible protective immunity in human opisthorchiasis. Parasite Immunology, 16: 279288.

    Google Scholar 

  • Amornpunt, S., Sarasombath, S. & Sirisinha, S. 1991. Production and characterization of monoclonal antibodies against the excretory-secretory antigen of the liver fluke (Opisthorchis viverrini). International Journal for Parasitology, 21: 421–428.

    Article  PubMed  CAS  Google Scholar 

  • Apinhasmit, W. & Sobhon, P. 1996. Opisthorchis viverrini: effect of praziquantel on the adult tegument. Southeast Asian Journal of Tropical Medicine and Public Health, 27: 304–311.

    CAS  Google Scholar 

  • Chen-Minggang, Lu-Yao, Hua-Xiangjin and Mott, K.E. 1994. Progress in assessment of morbidity due to Clonorchis sinensis infection: a review of recent literature. Tropical Diseases Bulletin, 91: R7 - R65.

    Google Scholar 

  • Elkins, D.B., Haswell-Elkins, M.R., Mairiang, E. et al. 1990. A high frequency of hepatobiliary disease and suspected cholangiocarcinoma associated with heavy Opisthorchis viverrini infection in a small community in north-east Thailand. Transactions of the Royal Society of Tropical Medicine and Hygiene. 84: 715–719.

    Article  PubMed  CAS  Google Scholar 

  • Fang, Y.Y. 1994. Epidemiological characteristics of Clonorchis sinensis in Guangdong, China. Southeast Asian Journal of Tropical Medicine and Public Health, 25: 29 1295.

    Google Scholar 

  • Harinasuta, T., Pungpak, S. & Keystone, J.S. 1993. Trematode infections opisthorchiasis, clonorchiasis, fascioliasis and paragonimiasis. Infectious Disease Clinics of North America, 7: 699–716.

    PubMed  CAS  Google Scholar 

  • Haswell-Elkins, M.R., Mairiang, E., Mairiang, P. Chaiyakum, J., Chamadol, N., Loapaiboon, V., Sithithaworn, P. & Elkins, D.B. 1994. Cross-sectional study of Opisthorchis viverrini infection and cholangiocarcinoma in communities within a high-risk area in northeast Thailand. International Journal of Cancer, 59: 505509.

    Google Scholar 

  • Haswell-Elkins, M.R., Satarug, S., Tsuda, M. et al. 1994. Liver fluke infection and cholangiocarcinoma: model of endogenous nitric oxide and extragastric nitrosation in human carcinogenesis. Mutation Research, 305: 241–252.

    Article  PubMed  CAS  Google Scholar 

  • Hering-Hagenbeck, S. & Schuster, R. 1996. A focus of opisthorchiidosis in Germany. Applied Parasitology, 37: 260–265.

    PubMed  CAS  Google Scholar 

  • Hinz, E., Saowakontha, S. & Pipitgool, V. 1994. Opisthorchiasis control in northeast Thailand: proposal for a new approach. Applied Parasitology, 35: 118–124.

    PubMed  CAS  Google Scholar 

  • Itoh, M., Pairojkul, C., Thamawit, W., Sithithaworn, P., Tiwawech, D., Uttaravicien, T., Shirai, T. & Ito, N. 1994. Association of antibodies to Opisthorchis viverrini with hepatobiliary disease in northeast Thailand. American Journal of Tropical Medicine and Hygiene, 51: 424–429.

    PubMed  CAS  Google Scholar 

  • Komiya, Y. 1966. Clonorchis and clonorchiasis. Advances in Parasitology, 4: 53–105.

    Article  CAS  Google Scholar 

  • Koompirochana, C., Sonakul, D., Chinda, K. & Stitnimankarn, T. 1978. Opisthorchiasis: A clinicopathologic study of 154 autopsy cases. Southeast Asian Journal of Tropical Medicine and Public Health, 9: 60–64.

    Google Scholar 

  • Lee, J.H., Rim, H.J. & Bak, U.B. 1993. Effect of Clonorchis sinensis infection and dimethylnitrosamine administration on the induction of cholangiocarcinoma in Syrian golden hamsters. Korean Journal of Parasitology, 31: 21–30.

    Article  PubMed  CAS  Google Scholar 

  • Lee, J.H., Yang, H.M., Bak, U.B. & Rim, H.J. 1994. Promoting role of Clonorchis sinensis infection on induction of cholangiocarcinoma during two-step carcinogenesis. Korean Journal of Parasitology, 32: 13–18.

    Article  PubMed  CAS  Google Scholar 

  • Lin, Y.L., Chen, E.R. & Yen, C.M. 1995. Antibodies in serum of patients with clonorchiasis before and after treatment. Southeast Asian Journal of Tropical Medicine and Public Health, 26: 114–119.

    PubMed  CAS  Google Scholar 

  • Liu, Y.S., Du, W.P., Wu, Y.M., Chen, Y.G., et al. 1995. Application of dot-immunogoldsilver staining in the diagnosis of clonorchiasis. Journal of Tropical Medicine and Hygiene, 98: 151–154.

    PubMed  CAS  Google Scholar 

  • MacLean, J.D., Arthur, J.R., Ward, B.J., Gyorkos, T.W., Curtis, M.A. & Kokoskin, E. 1996. Common-source outbreak of acute infection due to the North American liver fluke Metorchis conjunctus. Lancet, 347: 154–158.

    Article  CAS  Google Scholar 

  • Mairiang, E., Haswell-Elkins, M.R., Mairiang, P., Sithithaworn, P. & Elkins, D.B. 1993. Reversal of biliary tract abnormalities associated with Opisthorchis viverrini infection following praziquantel treatment. Transactions of the Royal Society of Tropical Medicine and Hygiene, 87: 194–197.

    Article  PubMed  CAS  Google Scholar 

  • Na-Bangchang, K., Karbwang, J., Pungpak, S., Radomyos, B. & Bunnag, D. 1993. Pharmacokinetics of praziquantel in patients with opisthorchiasis. Southeast Asian Journal of Tropical Medicine and Public Health, 24: 717–723.

    PubMed  CAS  Google Scholar 

  • Peng, H.W., Chao, H.L. & Fan, P.C. 1993. Imported Opisthorchis viverrini and parasite infections from Thai labourers in Taiwan. Journal of Helminthology, 67: 102–106.

    Article  PubMed  CAS  Google Scholar 

  • Pungpak, S., Chalermrut, K., Harinasuta, T., Viravan, C., Schelp, P.F., Hempfling, A., Schlattmann, P. & Bunnag, D. 1994.Opisthorchis viverrini infection in Thailand: symptoms and signs of infection–a population-based study. Transactions of the Royal Society of Tropical Medicine and Hygiene, 88: 561–564.

    Google Scholar 

  • Pungpak, S., Viravan, C., Radomyos, B., Chalermrut, K., Yemput, C., Plooksawasdi, W., Ho, M., Harinasuta, T. & Bunnag, D. 1997. Opisthorchis viverrini infection in Thailand: studies on the morbidity of the infection and resolution following praziquantel treatment. American Journal of Tropical Medicine and Hygiene, 56: 311–314.

    CAS  Google Scholar 

  • Rim, J.H. 1982. Clonorchiasis. In CRC Handbook Series in Zoonoses, Section C: Parasitic Zoonoses, Volume Ill (Editor in chief: J.H. Steele, volume editors: G. V. Hillyer and C.E. Hopla). CRC Press, Inc., Boca Raton, Florida. pp. 17–32.

    Google Scholar 

  • Rim, H.J. 1982. Opisthorchiasis. In CRC Handbook Series in Zoonosis, Section C: Parasitic Zoonoses, Volume Ill (Editor in chief: J.H. Steele, volume editors: G. V. Hillyer and C.E. Hopla). CRC Press, Inco., Boca Raton, Florida. pp. 109–121.

    Google Scholar 

  • Rim, H.J. 1986. The current pathobiology and chemotherapy of clonorchiasis. Korean Journal of Parasitology, 24 (suppl.): 1–141.

    Article  PubMed  Google Scholar 

  • Rim, H.J. 1990. Clonorchiasis in Korea. Korean Journal of Parasitology, 28 (Suppl.): 63–78.

    Article  PubMed  Google Scholar 

  • Riganti, M., Pungpak, S., Punpoowong, B., Bunnag, D. & Harinasuta, T. 1989. Human pathology of Opisthorchis viverrini infection: A comparison of adults and children. Southeast Asian Journal of Tropical Medicine and Public Health, 20: 95–100.

    PubMed  CAS  Google Scholar 

  • Rodriguez, M., J.D., Gomez Lince, L.F. and Montalvan, C., J.A. 1949. EI Opisthorchis guayaquilensis (Una nueva especie de Opisthorchis encontrada en el Ecuador. Rivista Ecuatoriana de Higiene y Medicina Tropical, 6: 11–24.

    Google Scholar 

  • Sadun, E.H. 1955. Studies on Opisthorchis viverrini in Thailand. American Journal of Hygiene, 62: 81–115.

    PubMed  CAS  Google Scholar 

  • Saowakontha, S., Pipitgool, V., Pariyanonda, S., Tesana, S., Rojsathaporn, K. & Intarakhao, C. 1993. Field trials in the control of Opisthorchis viverrini with an integrated programme in endemic areas of northeast Thailand. Parasitology, 106: 283–288.

    Article  PubMed  Google Scholar 

  • Satarug, S., Haswell-Elkins, M.R., Tsuda, M. et al. 1996. Thiocyanate-independent nitrosaion in humans with carcinogenic parasite infection. Carcinogenesis, 17: 1075–1081.

    Article  PubMed  CAS  Google Scholar 

  • Schwartz, D.A. 1980. Helminths in the induction of cancer: Opisthorchis viverrini, Clonorchis sinensis and cholangiocarcinoma. Tropical and Geographical Medicine, 32: 95–100.

    PubMed  CAS  Google Scholar 

  • Shekhar, K.C., Nazarina, A.R., Lee, S.H. & Pathmanathan, R. 1995. Clonorchiasis/opisthorchiasis case reports and review. Medical Journal of Malaysia, 50: 182–186.

    PubMed  CAS  Google Scholar 

  • Sirisinha, S., Chawengkirttikul, R., Haswell-Elkins, M.R., Elkins, D.B., Kaewkes, S. & Sithithaworn, P. 1995. Evaluation of a monoclonal antibody-based enzyme linked immunosorbent assay for the diagnosis of Opisthorchis viverrini infection in an endemic area. American Journal of Tropical Medicine and Hygiene, 52: 521–524.

    PubMed  CAS  Google Scholar 

  • Sirisinha, S., Chawengkirttikul, R., Sermswan, R., Amornpant, S., Mongkolsuk, S. & Panyim, S. 1991. Detection of Opisthorchis viverrini by monoclonal antibody-based ELISA and DNA hybridization. American Journal of Tropical Medicine and Hygiene, 44: 140–145.

    PubMed  CAS  Google Scholar 

  • Sirisinha, S., Sahassananda, D., Bunnag, D. & Rim, H.J. 1990 Immunological analysis of Opisthorchis and Clonorchis antigens. Journal of Helminthology, 64: 133–138.

    Article  PubMed  CAS  Google Scholar 

  • Sithithaworn, P., Haswell-Elkins, M.R., Mairiang, P., Satarug, S., Mairiang, E., Vatanasapt, V. & Elkins, D.B. 1994. Parasite-associated morbidity: liver fluke infection and bile duct cancer in northeast Thailand. International Journal for Parasitology, 24: 833–843.

    Article  PubMed  CAS  Google Scholar 

  • Sithithaworn, P., Tesana, S., Pipitgool, V. et al. 1991. Quantitative post-mortem study of Opisthorchis viverrini in man in northeast Thailand. Transactions of the Royal Society of Tropical Medicine and Hygiene, 85: 765–768.

    Article  PubMed  CAS  Google Scholar 

  • Thamavit, W., Pairojkul, C., Tiwawech, D., Shirai, T. & Ito, N. 1994. Strong promoting effect of Opisthorchis viverrini infection on dimethylnitrosamine-initiated hamster liver. Cancer Letters, 78: 121–125.

    Article  PubMed  CAS  Google Scholar 

  • Ya-Ling, L., Eng-Rin, C. and Chuan-Min, Y. 1995. Antibodies in serum of patients with clonorchiasis before and after treatment. Southeast Asian Journal of Tropical Medicine and Public Health, 26: 114–119.

    Google Scholar 

  • Yen, C.M., Chen, E.R., Hou, M.F. & Chang, J.H. 1992. Antibodies of different immunoglobulin isotypes in serum and bile of patients with clonorchiasis. Annals of Tropical Medicine and Parasitology, 86: 263–269.

    PubMed  CAS  Google Scholar 

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© 1999 Springer Science+Business Media Dordrecht

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Kumar, V. (1999). Clonorchiasis and opisthorchiasis. In: Trematode Infections and Diseases of Man and Animals. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-3594-0_6

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  • DOI: https://doi.org/10.1007/978-94-017-3594-0_6

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-5152-3

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