Abstract
The herbicide Roundup® whose active ingredient is glyphosate (N-[phosphonomethy1]-glycine) was introduced as a broad spectrum, post emergent herbicide in 1974. Extensive research by a number of groups showed that glyphosate’s herbicidal activity resulted from inhibition of the enzyme 5-enolpyruvyl-shikimate-3-phosphate synthase (EPSPS) a key enzyme in the shikimate pathway that is responsible for the biosynthesis of aromatic amino acids in plants and microbes (reviewed, Franz et al., 1997).
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Heck, G.R., CaJacob, C.A., Padgette, S.R. (2003). Discovery, Development, and Commercialization of Roundup Ready® Crops. In: Vasil, I.K. (eds) Plant Biotechnology 2002 and Beyond. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-2679-5_22
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DOI: https://doi.org/10.1007/978-94-017-2679-5_22
Publisher Name: Springer, Dordrecht
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