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Sequence Analysis of CTP:Phosphocholine Cytidylyltransferase cDNA from Arabidopsis Thaliana

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Physiology, Biochemistry and Molecular Biology of Plant Lipids
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Abstract

Phosphatidylcholine (PC) is the major lipid component of eukaryotic membranes. The pathway of de novo synthesis of PC is composed of consecutive three reactions, and CTP:phosphocholine cytidylyltransferase (CT; EC 2.7.7.15) catalyzes the second reaction, which is generally believed to be the key regulatory step of the pathway. In mammals CT exists both as an active membrane-bound form and as an inactive cytosolic form, and the interconversion between them is believed to regulate the overall formation of PC. As one of the steps to elucidate the regulatory mechanism for PC synthesis in plants, the sequence of A. thaliana CT cDNA was determined.

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References

  • Kalmar, G.B., Kay, R.J., LaChance, A., Aebersold, R., and Cornell, R.B. (1990) Cloning and expression of rat liver CTP:phosphocholine cytidylyltransferase: an amphipathic protein that controls phosphatidylcholine synthesis, Proc. Natl. Acad. Sci. USA. 87, 6029–6033.

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© 1997 Springer Science+Business Media Dordrecht

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Cho, S.H., Choi, SB., Kim, J.C., Lee, KW. (1997). Sequence Analysis of CTP:Phosphocholine Cytidylyltransferase cDNA from Arabidopsis Thaliana . In: Williams, J.P., Khan, M.U., Lem, N.W. (eds) Physiology, Biochemistry and Molecular Biology of Plant Lipids. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-2662-7_117

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  • DOI: https://doi.org/10.1007/978-94-017-2662-7_117

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-4784-7

  • Online ISBN: 978-94-017-2662-7

  • eBook Packages: Springer Book Archive

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