Abstract
In the process of vision, light stimuli are converted into neural information by a membrane protein called rhodopsin that initiates the transduction process. The primary photochemical event involves the photoconversion of rhodopsin into a metastable intermediate called bathorhodopsin [1,2]. The chromophore of rhodopsin is an 11-cis retinylidene prosthetic group covalently bound to the surrounding opsin protein via a protonated Schiff base (PSB) linkage to a specific lysine residue, Lys296 (Fig. 1). The absorption of light induces the isomerization of the 11-cis-retinal chromophore to an all-trans configuration in bathorhodopsin.
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Buda, F., Touw, S.I.E., de Groot, H.J.M. (2001). An ab-initio molecular dynamics modeling of the primary photochemical event in vision. In: Kiihne, S.R., de Groot, H.J.M. (eds) Perspectives on Solid State NMR in Biology. Focus on Structural Biology, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-2579-8_10
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DOI: https://doi.org/10.1007/978-94-017-2579-8_10
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