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Integration of Micro-Optical Systems for Fluorescence Detection in µTAS Applications

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Micro Total Analysis Systems 2000

Abstract

Microfabrication technology has become a widely used approach in the development of miniaturized systems for chemical analysis in microfluidic channels. Moreover, microfabrication technology can be used to integrate microlens and aperture arrays directly onto microchemical chips. Such optical elements enable the realization of optical functions for illumination, collection and signal filtering, necessary for fluorescence detection. A new completely integrated microfluidic/micro-optic device is presented, in which refractive microlens arrays (with a diameter of a couple of hundred µm) and aluminum aperture arrays are integrated on both sides of a chemical chip. The chip is composed of two 4” thermally bonded pyrex glass wafers in which microfluidic networks are etched. The microchannels are 25 µm deep and 50 µm wide. The overall thickness of the chip with the detection system is less than 2 mm.

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© 2000 Springer Science+Business Media Dordrecht

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Roulet, JC., Herzig, H.P., Verpoorte, E., de Rooij, N.F., Dändliker, R. (2000). Integration of Micro-Optical Systems for Fluorescence Detection in µTAS Applications. In: van den Berg, A., Olthuis, W., Bergveld, P. (eds) Micro Total Analysis Systems 2000. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-2264-3_38

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  • DOI: https://doi.org/10.1007/978-94-017-2264-3_38

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-5496-8

  • Online ISBN: 978-94-017-2264-3

  • eBook Packages: Springer Book Archive

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