Abstract
The ability to separate and identify cells and other particulate matter is a fundamental requirement of microsystems designed for biomedical and other applications. Here we describe a method that combines dielectrophoresis and field-flow fractionation to separate and identify particles in a microfluidic environment. This method is applicable not only to the analysis of cellular and other particulate analytes but also to the detection of toxins using sensitized test particles. We show proof of principle by achieving differential separation of human peripheral blood mononuclear cell subtypes in a microsystem based on the method.
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© 2000 Springer Science+Business Media Dordrecht
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Vykoukal, J. et al. (2000). A Combined Dielectrophoretic and Field-Flow Fractionation Microsystem for Biomedical Separation and Analysis. In: van den Berg, A., Olthuis, W., Bergveld, P. (eds) Micro Total Analysis Systems 2000. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-2264-3_29
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DOI: https://doi.org/10.1007/978-94-017-2264-3_29
Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-5496-8
Online ISBN: 978-94-017-2264-3
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