Abstract
Flow-through microcalorimetry on chemical reactions with low reaction enthalpy at low concentrations needs a reactor volume considerably larger than 2μ1 to provide enough substance for sufficiently high signal levels. Additionally, in microcalorimeters using thin-film thermopiles the thermoelectrical signal output can be increased by simply enhancing the number of thermocouples connected in series. We present a flow-through chip calorimeter with a reactor volume of 10μ1 and a thermopower of 64 mV/K aimed at calorimetry on biochemical and especially enzymatically catalyzed reactions.
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References
B. Xie, M. Mecklenburg, B. Danielsson, O. Oehman, F. Winquist; Microbiosensor based on an Integrated Thermopile; Anal. Chim. Acta, 299 (1994) 165–170
J. Lerchner, A. Wolf, G. Wolf; Recent developments in Integrated Circuit calorimetry; J.Therm.Anal.Cal., 56 (1999) 241–251
J.M. Köhler, M. Zieren; Chip reactor for microfluid calorimetry; Thermochim. Acta, 310 (1998) 25–35
E. KeBler, J. Müller, F. Völklein et al.; First Measuring Results Concerning a new Thin-Film Absolute Radiometer; SPIE vol.1712 14th Symposium on Photonic Measurements (1992)
A. van Herwaarden, P.M. Sarno, J.W. Gardner, P. Bataillard; Liquid and gas micro-calorimeters for (bio)chemical measurements; Sens. Act. A, 43 (1994) 24–30
A. Wolf, A. Weber, R. Hüttl, J. Lerchner, G. Wolf; Sequential flow injection analysis based on calorimetric detection; Thermochim. Acta, 337 (1999) 27–38
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© 2000 Springer Science+Business Media Dordrecht
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Zieren, M., Willnauer, R., Köhler, J.M. (2000). Flow-Through Chip Calorimeter Based on Bisb/Sb-Thin-Film Thermopiles with a Thermopower of 64 mV/K. In: van den Berg, A., Olthuis, W., Bergveld, P. (eds) Micro Total Analysis Systems 2000. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-2264-3_15
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DOI: https://doi.org/10.1007/978-94-017-2264-3_15
Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-5496-8
Online ISBN: 978-94-017-2264-3
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