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The Evaluation of Hypoxia in Diabetes

  • Chapter
Imaging of Hypoxia

Part of the book series: Developments in Nuclear Medicine ((DNUM,volume 33))

  • 163 Accesses

Abstract

The prognosis for diabetic patients who maintain glycemic control through diet, exercise or the use of insulin or other glycemic control medication remains very good. However, even in the presence of good disease control, long term diabetes patients are prone to a variety of complications that contribute to morbidity and mortality. The majority of these complications have their basis in macrovascular and microvascular changes that appear to arise in susceptible individuals, and to some extent in all diabetic patients regardless of the care taken in the management of their disease. Among the major complications faced by diabetic patients are retinopathy, neuropathy and the diabetic foot syndrome. In each of these conditions an underlying microvascular pathology is evident. This microangiopathy has a multifunctional pathogenesis although it is believed that a primary mechanism is at work from the beginning of diabetes which contributes to progressive vascular disease.

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Authors
  1. John R. Mercer
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  2. Hui Liu
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  1. Section Radiopharmacy, Interdisciplinary PET-Center, Eberhard-Karls University, Tübingen, Germany

    Hans-Jürgen Machulla

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Mercer, J.R., Liu, H. (1999). The Evaluation of Hypoxia in Diabetes. In: Machulla, HJ. (eds) Imaging of Hypoxia. Developments in Nuclear Medicine, vol 33. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-1828-8_8

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  • DOI: https://doi.org/10.1007/978-94-017-1828-8_8

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