Abstract
The possible involvement of radical cations in enzymatic oxidations is a problem of current interest. A simple approach to address this problem is that of investigating suitable substrates which when converted into radical cations produce a products pattern completely different from that expected when other mechanisms, i.e. involving atom transfer or ionic steps, take place.’ In the last few years we have applied this approach to the study of the mechanism of the side-chain hydroxylation of alkylaromatics by cytochrome P-450 and of the sulfoxidation of aromatic sulfides by cytochrome P-450 and peroxidases. The most recent results of this study will be described in this paper.
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Baciocchi, E., Bietti, M., Ioele, M., Lanzalunga, O., Steenken, S. (1997). Mechanisms of the Oxidation of Alkylaromatics and Aromatic Sulfides by Cytochrome P-450 and Peroxidases. In: Minisci, F. (eds) Free Radicals in Biology and Environment. NATO ASI Series, vol 27. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-1607-9_8
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