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Signal Transduction Mechanisms in Protozoa

  • Chapter
Book cover Cell Signalling in Prokaryotes and Lower Metazoa

Summary

Although protozoa are unicellular eukaryotes, they have developed signalling mechanisms to modulate fundamental activities such as acquisition of nutrients and reproduction. However, our knowledge of signal transduction events in protozoa has lagged behind advances made in this field in more complex organisms. Nevertheless, evidence discussed in this review suggests that signal transduction events take place in protozoa by mechanisms that are similar to those present in higher eukaryotes, namely, binding of signalling molecules by specific receptors. This binding then results in the activation of specific signalling pathways. The latter have been studied in more detail in ciliates, in particular, in the opioid mechanism in Tetrahymena and Stentor, chemosensing in Paramecium and pheromone secretion in Euplotes. These data suggest that the complex signalling pathways present in metazoa originated in evolution from unicellular eukaryotes.

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Authors and Affiliations

  1. Rio Piedras Campus, University of Puerto Rico, San Juan, PR, USA

    Fernando L. Renaud

  2. Plattsburgh State University of New York, Plattsburgh, NY, USA

    José De Ondarza

  3. University of Camerino, Camerino, Italy

    Pierangelo Luporini

  4. Emory University School of Medicine, Atlanta, GA, USA

    Michael J. Marino

  5. University of Vermont, Burlington, VT, USA

    Judy Van Houten

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  1. Fernando L. Renaud
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  2. José De Ondarza
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  3. Pierangelo Luporini
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  4. Michael J. Marino
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  5. Judy Van Houten
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  1. School of Biology and Biochemistry, The Queen’s University of Belfast, Belfast, Northern Ireland

    Ian Fairweather

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Renaud, F.L., De Ondarza, J., Luporini, P., Marino, M.J., Van Houten, J. (2004). Signal Transduction Mechanisms in Protozoa. In: Fairweather, I. (eds) Cell Signalling in Prokaryotes and Lower Metazoa. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0998-9_3

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  • DOI: https://doi.org/10.1007/978-94-017-0998-9_3

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