Abstract
Life and environment are in a constant interaction, and temperature plays in this a crucial role. It affects the rate of all cellular reactions and it determines the survival of the organisms. Notoriously sensitive to temperature is mammalian cell survival which is mainly limited to a narrow range of temperatures, from a few degrees to approximately 40°C. Cells differ in the range of temperatures that they can tolerate. This may change in time as a certain degree of adaptation is possible. It has been known that exposure to a sub-lethal temperature often leads to adaptations so that previously lethal temperatures are now tolerated. This response to heat shock has attracted considerable attention from molecular biologists over the last decade, which has resulted in a rapid accumulation of data providing considerable insights not only into the molecular basis of thermotolerance, but also into stress physiology in general. The heat shock response is now known to occur from bacteria to man (Schlesinger et al. 1982). It is accompanied by a transient reprogramming of cellular activities to ensure the cell’s survival by stimulating defence mechanisms and by protecting essential cell components against the heat damage.
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© 1998 Springer Science+Business Media Dordrecht
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Souren, J.E.M., Van Wijk, R. (1998). Luminometry in Cellular Stress Research. In: Chang, JJ., Fisch, J., Popp, FA. (eds) Biophotons. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0928-6_5
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DOI: https://doi.org/10.1007/978-94-017-0928-6_5
Publisher Name: Springer, Dordrecht
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