Abstract
The potentiated sulfonamides are combinations of two antibacterial drugs, a sulfonamide and a pyrimidine potentiator. The combination is synergistic, that is, the antibacterial potency of the combination is greater than the sum of the potencies of the two separate drugs. This is because they act as competitive inhibitors of two successive steps in the synthetic pathway of folinic acid in bacteria.
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© 2000 Springer Science+Business Media Dordrecht
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Treves-Brown, K.M. (2000). Potentiated Sulfonamides. In: Applied Fish Pharmacology. Aquaculture, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0761-9_9
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DOI: https://doi.org/10.1007/978-94-017-0761-9_9
Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-4014-5
Online ISBN: 978-94-017-0761-9
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