Abstract
The role of dendritic cells (DCs) in T cell responses induced at the intestinal mucosa is unclear. Here, we demonstrate functional differences between DCs from Peyer’s patch (PP) and spleen (SP), such as the ability to induce T cell differentiation. In this study, antigen presentation by PP DCs induced both Thi and Th2 differentiation. PP DCs were found to induce increased IFN-γ production compared to SP DCs, suggesting that DCs residing in different tissues are capable of inducing distinct immune responses.
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References
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© 2002 Springer Science+Business Media Dordrecht
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Sato, A., Hashiguchi, M., Hachimura, S., Kaminogawa, S. (2002). The Role Dendritic Cells Play in the Cytokine Responses in Peyer’s Patches. In: Shirahata, S., Teruya, K., Katakura, Y. (eds) Animal Cell Technology: Basic & Applied Aspects. Animal Cell Technology: Basic & Applied Aspects, vol 12. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0728-2_38
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DOI: https://doi.org/10.1007/978-94-017-0728-2_38
Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-5934-5
Online ISBN: 978-94-017-0728-2
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