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Aging in C. elegans

  • Chapter
Aging of Organisms

Part of the book series: Biology of Aging and its Modulation ((BIMO,volume 4))

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Abstract

In the last decade of the 20th century one model organism has received more attention from gerontologists than any other, namely the free-living soil nematode Caenorhabditis elegans (C. elegans). We owe much of our general view of the genetic determination of lifespan to this organism. C. elegans became a popular organism for the analysis of complex biological problems following the pioneering work of Sidney Brenner and Sir John Sulston who determined the developmental cellular fate map [1]. It is also noted for the early work of Robert Horvitz and colleagues who used the cell lineage map to begin a genetic dissection of programmed cell death [2].

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  1. Buck Institute, Novato, CA, 94945, USA

    Anders Olsen, James N. Sampayo & Gordon J. Lithgow

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    Heinz D. Osiewacz

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Olsen, A., Sampayo, J.N., Lithgow, G.J. (2003). Aging in C. elegans . In: Osiewacz, H.D. (eds) Aging of Organisms. Biology of Aging and its Modulation, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0671-1_7

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