Abstract
The natural history of primary sclerosing cholangitis (PSC) is, to say the least, puzzling in its variability, in terms of age of onset, symptoms and prognosis.[1–2] As a matter of fact there are several, unfortunately independent areas of observation: the Doctor following a patient with Ulcerative Colitis (UC) or Crohn’s Disease (CD), who sees quite a benign increase of serum alkaline phosphatase (sALP) and is not worried about it, the Hepatologist who is quite happy to have found a rare disease, or the Endoscopist willing to perform exploration and diagnosis, but little interested in the radiologic aspect.
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D’Innocenzo, S., Russo, F., Miglioresi, L., Bacosi, M., Ricci, G.L. (2002). The Evolutionary Pattern of Primary Sclerosing Cholangitis: From a Benign to Severe Disease. In: Farinon, A.M. (eds) Advances in Abdominal Surgery 2002. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0637-7_5
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