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Pancreas Procurement from Cadaveric Donors of Multiple Grafts

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Book cover Advances in Abdominal Surgery 2002

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Abstract

Background This paper describes a modified technique for concurrent procurement of pancreas, liver, kidneys and isolated small bowel. The main distinctive features of this procedure are avoidance of direct portal perfusion and simplification of in vivo and bench-work dissection.

Methods Between December 1997 and December 2001, 893 grafts were retrieved in 223 multiorgan procurements.

Results All procurements progressed expeditiously and no graft sustained injuries precluding transplant. Vascular variations were identified in 82 donors (36.7%). A total of 64 pancreata were transplanted by our team, including 48 simultaneous pancreas-kidney transplants, 6 simultaneous cadaveric pancreas living kidney transplants and 10 pancreas transplants alone. One additional pancreas was procured and shipped to another center for isolated grafting. Three pancreata were employed for islet cell transplantation and 96 for islet cell isolation and in vitro viability and secretion studies. The remaining 59 pancreata were discarded. A total of 181 livers (174 full size grafts, 6 split grafts and 1 reduced size graft), 419 kidneys and 2 isolated small bowels were also procured and transplanted at 17 different institutions. In 20 instances the liver was not allocated to our center. Nineteen liver teams (95%), from 9 different institutions, agreed to procure their grafts according to our method. Seven procurements were done entirely by our team, and 12 by a surgeon from the liver transplant team assisted by one of us.

Conclusions This procurement technique is quick, simple, safe, standardized, flexible and at least as effective as other “conventional” procedures. Since one team can procure all abdominal organs, this technique may facilitate organization and reduce costs of multiorgan procurement.

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Authors and Affiliations

  1. Department of Surgery and Organ Transplantation, University of Pisa, Pisa, Italy

    Ugo Boggi, Fabio Vistoli, Marco Del Chiaro, Andrea Pietrabissa, Gabriele Catalano, Piero Marchetti & Franco Mosca

  2. Endocrinology and Metabolism, Section of Metabolism, University of Pisa, Pisa, Italy

    Stefano Del Prato

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  1. Ugo Boggi
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Editors and Affiliations

  1. Department of Surgery, University of Rome “Tor Vergata”, Rome, Italy

    Attilio Maria Farinon (Professor of Surgery and Chairman) (Professor of Surgery and Chairman)

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Boggi, U. et al. (2002). Pancreas Procurement from Cadaveric Donors of Multiple Grafts. In: Farinon, A.M. (eds) Advances in Abdominal Surgery 2002. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0637-7_26

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  • DOI: https://doi.org/10.1007/978-94-017-0637-7_26

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-6135-5

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