Abstract
Polyunsaturated fatty acids (PUFAs) with more than 18 carbons in length are essential constituents functioning in membrane fluidity, signal transduction, and eicosanoid production. The biosynthesis of PUFAs requires an alternating series of desaturation and elongation reactions.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Beaudoin, F., Michaelson, L.V., Hey, S.J., Lewis, M.J., Shewry, P.R., Sayanova, O.and Napier, J.A. (2000) Heterologous reconstitution in yeast of the polyunsaturated fatty acid biosynthetic pathway. Proc. Natl. Acad. Sci. USA 97, 6421–6426
Han, J., Lühs, W., Sonntag, K., Zähringer, U., Borchardt, D.S., Wolter, F.P., Heinz, E. and Frentzen, M. (2001) Functional characterization of 3-ketoacyl-CoA synthase genes from Brassica napus L. Plant Mol. Biol. 46, 229–239
Leonard, A.E., Bobik, E.G., Dorado, J., Kroeger, P.E., Chuang, L.-T., Thurmond, J.M., Parker-Barnes, J.M., Das, T., Huang, Y.-S., and Mukerji, P. (2000) Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids. Biochem. J. 350, 765–770
Parker-Barnes, J.M., Das, T., Bobik, E., Leonard, A.E., Thurmond, J.M., Chuang, L.-T., Huang, Y.-S. and Mukerji, P. (2000) Identification and characterization of an enzyme involved in the elongation of n-6 and n-3 polyunsaturated fatty acids. Proc. Natl. Acad. Sci. USA 97, 8284–8289
Qi, B., Beaudoin, F., Fraser, T., Stobart, A.K., Napier, J.A. and Lazarus, C.M. (2002) Identification of a cDNA encoding a novel C18–49 polyunsaturated fatty acid-specific elongating activity from the docosahexaenoic acid (DHA)-producing microalga, Isochrysis galbana. FEBS Letters 510, 159–165
Zank, T.K., Zähringer, U., Lerchl, L. and Heinz, E. (2000) Cloning and functional expression of the first plant fatty acid elongase specific for 46-polyunsaturated fatty acids. Bioc. Soc. Trans. 28, 654–658
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2003 Springer Science+Business Media Dordrecht
About this chapter
Cite this chapter
Han, J., Wolter, F.P., Jaworski, J.G., Frentzen, M. (2003). Brassica KCS is Capable of Elongating Polyunsaturated Fatty Acids. In: Murata, N., Yamada, M., Nishida, I., Okuyama, H., Sekiya, J., Hajime, W. (eds) Advanced Research on Plant Lipids. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0159-4_11
Download citation
DOI: https://doi.org/10.1007/978-94-017-0159-4_11
Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-6210-9
Online ISBN: 978-94-017-0159-4
eBook Packages: Springer Book Archive