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Capillary Electrophoresis/Nucleic Acid Probe Identification of Biological Warfare Agent Simulants

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Part of the book series: NATO ASI Series ((ASDT,volume 30))

Abstract

The goal of this research is to develop rapid, robust assays and equipment that are amenable to field detection and identification of BW agent attacks. The system must detect BW agents at extremely low concentrations with no false alarms and operate under battlefield conditions [1]. Typically high volume air samplers are required to concentrate high volumes of air into liquid samples, often by a factor of 106, for analysis [2]. To provide the earliest possible warning and maximum protection to personnel, the field detection and identification equipment (and associated assay chemistry) must be highly specific, ultra-sensitive, and very reliable [3].

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References

  1. For a review of the nature and threat of biological warfare see Cole. Leonard A. The Spectre of Biological Weapons, Scientific American, December 1996.

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  2. White, L. A., Hadley, D. J., Davids, D. E., and Naylor, R. Appl Micmbiol. 29, 335–339, 1975.

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© 2000 Springer Science+Business Media Dordrecht

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Boulet, C.A., Hung, G., Bader, D.E., Duck, P., Wishart, P., Lai-How, A. (2000). Capillary Electrophoresis/Nucleic Acid Probe Identification of Biological Warfare Agent Simulants. In: Stopa, P.J., Bartoszcze, M.A. (eds) Rapid Methods for Analysis of Biological Materials in the Environment. NATO ASI Series, vol 30. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-9534-6_8

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  • DOI: https://doi.org/10.1007/978-94-015-9534-6_8

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-5455-5

  • Online ISBN: 978-94-015-9534-6

  • eBook Packages: Springer Book Archive

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