Abstract
Ginseng plants (Panax spp.) have been used as a healing drug and a health tonic in oriental countries such as China, Japan and Korea since ancient times. It has been reported that ginseng has many beneficial bioactive effects on human health, such as anti-tumor, anti-stress, anti-aging and enhancing immune functions. Ginseng saponins and polysaccharides have been identified as the principal bioactive ingredients of ginseng. For example, ginsenosides have physiological and pharmacological effects such as cardio-protective, immunomodulatory, anti-fatigue, and hepato-protective activities.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Wu, J. and Zhong, J.J. (1999) Production of ginseng and its bioactive components in plant cell culture: current technological and applied aspects. J. Biotechnol. 68, 89–99.
Sticher, 0. (1998) Getting to the root of ginseng. CHEMTECH. 28, 26–32.
Furuya, T. and Ushiyama, K. (1994) Ginseng production in cultures of Panax ginseng cells. In: P.
Shargool and T.T. Ngo (ed.), Biotechnological applications of plant cultures,pp. 1–22, CRC Press, Boca Raton, Fla.
Kieran, P.M., MacLoughlin, P.F. and Malone, D.M. (1997) Plant cell suspension cultures: some engineering considerations. J. Biotechnol. 59, 39–52.
Zhong, J.J. and Yoshida, T. (1995) High-density cultivation of Perilla frutescens cell suspensions for anthocyanin production: effects of sucrose concentration and inoculum size. Enzyme Microb. Technol. 17, 1073–1079
Zhang, Y.H. and Zhong, J.J. (1997) Hyper-production of ginseng saponin and polysaccharide by high density cultivation of Panax notoginseng cells. Enzyme Microb. Technol. 21, 59–63.
Zhong, J.J. and Wang, D.J. (1996) Improvement of cell growth and production of ginseng saponin and polysaccharide in suspension cultures of Panax notoginseng: Cu’ effects. J. Biotechnol. 46, 69–72.
Yamaguchi, H., Kasai, R., Matsuura, H., Tanaka, 0. and Fuwa, T. (1988) High-performance liquid chromatographic analysis of acidic saponins of ginseng and related plants. Chem. Pharm. Bull. 36, 3468–3473.
Ushiyama, K. and Hibino, K. (1997) Commercial production of ginseng by plant cell culture. Am. Chem. Soc. 213 National Meeting, San Francisco, CA, Abstract, Pt. 1, AGFD 057.
Zheng, G.Z. and Yang, C.R. (1994) Panax notoginseng: biology and application. Sci Press, Beijing. ( Chinese )
Zhong, J.J., Chen, F. and Hu, W.W. (1999) High density cultivation of Panax notoginseng cells in stirred bioreactors for the production of ginseng biomass and ginseng saponin. Process Biochem.,in press.
Wang, S.J. and Zhong, J.J. (1996) A novel centrifugal impeller bioreactor. I. Fluid circulation, mixing, and liquid velocity profiles. Biotechnol. Bioeng. 51, 511–519.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2000 Springer Science+Business Media Dordrecht
About this chapter
Cite this chapter
Zhong, J.J. (2000). Production of Ginseng Saponins by Cell Suspension Cultures of Panax Notoginseng in Bioreactors. In: Oleszek, W., Marston, A. (eds) Saponins in Food, Feedstuffs and Medicinal Plants. Proceedings of the Phythochemical Society of Europe, vol 45. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-9339-7_17
Download citation
DOI: https://doi.org/10.1007/978-94-015-9339-7_17
Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-5341-1
Online ISBN: 978-94-015-9339-7
eBook Packages: Springer Book Archive