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Carbohydrates pp 228–257Cite as

Oligosaccharide geometry and dynamics

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Abstract

As with proteins and nucleic acids, the structure and dynamics of oligosaccharides can be quite important to their biological function. Many oligosaccharides, such as the carbohydrate portions of glycoproteins, are involved in molecular recognition, in which their particular structures and conformations are recognized by other proteins which specifically bind to them. Furthermore, since many of the disaccharides are the repeat units of polysaccharides, their dynamical behavior and conformational preferences largely shape the properties of these larger polymers as well. For these reasons, it would be most desirable to develop a general understanding of oligosaccharide conformations and dynamics. While a great deal is known about the primary structures of oligosaccharides (Doubet et al., 1989), it has unfortunately proven to be quite difficult to study their conformations and dynamics experimentally, and this class of molecules is generally much more poorly known than other types of biopolymers.

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  1. Centre for Chemical Sciences, Royal Holloway, University of London, UK

    Paul Finch

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Brady, J. (1999). Oligosaccharide geometry and dynamics. In: Finch, P. (eds) Carbohydrates. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-9281-9_6

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