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Molecular and General Genetics

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Thermophilic Moulds in Biotechnology

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Abstract

As eukaryotes, filamentous fungi represent very peculiar characteristics of higher organisms: they have a complex genome organised in many chromosomes, the total length reaching 2–5 × 107 base pairs in the haploid forms of Ascomycetes and Basidiomycetes. Apart from the consequences brought about by such complexity, fungal genomic studies have been proved to be very useful in a variety of academic and biotechnological investigations. In fact, filamentous fungi possess a number of properties, which make them important scientifically as well as economically. The latter can be illustrated by a large variety of products that are produced by filamentous fungi such as organic acids, antibiotics, and numerous industrial enzymes. They are also used as food (mushrooms, truffles), and in the production of food additives (e.g. the meat extender ‘Quorn’) and condiments (e.g. Soy sauce). The recent research and development efforts have yielded a polyketide, mevilonin produced by Aspergillus terreus, which is used in the treatment of hyperchloesterolaemia. Stierle et al. (115) have reported that taxol from Taxomyces andreanae has antitumor activity. It has been suggested that phytase from Aspergillus spp. improves the quality of animal feed by releasing phosphate from phytate that enhances phosphate availability.

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Authors
  1. M. O. Azevedo
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  2. M. S. S. Felipe
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  3. T. Satyanarayana
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Editors and Affiliations

  1. Department of Microbiology, CBSH, G.B. Pant University of Agriculture & Technology, Pantnagar, India

    B. N. Johri

  2. Department of Microbiology, University of Delhi South Campus, New Delhi, India

    T. Satyanarayana

  3. Department of General Microbiology, University of Copenhagen, Copenhagen, Denmark

    J. Olsen

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Azevedo, M.O., Felipe, M.S.S., Satyanarayana, T. (1999). Molecular and General Genetics. In: Johri, B.N., Satyanarayana, T., Olsen, J. (eds) Thermophilic Moulds in Biotechnology. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-9206-2_13

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