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Analgesics

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Clinical Nephrotoxins

Abstract

Renal failure, induced by the longstanding and inappropriate consumption of analgesic mixtures remains a serious problem in several countries. The initial reports [1–4], observing that phenacetin was present in most abused analgesics, held this substance solely responsible for the development of what was called “phenacetin nephritis”. In the late 1970’s, it became apparent that the abuse of different kinds of analgesic mixtures induced severe renal damage, whether they contained phenacetin or not. The disease was more appropriately named analgesic nephropathy.

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Authors
  1. Monique M. Elseviers
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  2. Marc E. De Broe
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Editor information

Editors and Affiliations

  1. Division of Nephrology and Hypertension, University of Antwerp, Belgium

    M. E. De Broe  & G. A. Verpooten  & 

  2. Department of Medicine, The Oregon Health Sciences University, Portland, Oregon, 97201, USA

    G. A. Porter

  3. Division of Nephrology, The Oregon Health Sciences University, Portland, Oregon, 97201, USA

    W. M. Bennett

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Elseviers, M.M., De Broe, M.E. (1998). Analgesics. In: De Broe, M.E., Porter, G.A., Bennett, W.M., Verpooten, G.A. (eds) Clinical Nephrotoxins. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-9088-4_13

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  • DOI: https://doi.org/10.1007/978-94-015-9088-4_13

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-015-9090-7

  • Online ISBN: 978-94-015-9088-4

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