Open Heart Surgery 1955-mid 1970s

  • Catherine A. Neill
  • Edward B. Clark
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 163)


Today, in the 1990s, the greatest volume of both cardiac surgery and interventional cardiology is performed in adults with acquired heart disease, especially that due to coronary atherosclerosis. It is sometimes forgotten that the pioneering efforts of both open heart surgery and interventional catheterisation began with children. Just as closed heart surgery for children ushered in the dawn of therapy, so did cardiopulmonary bypass begin with the young. For both children and adults with heart disease, cardiopulmonary bypass and Rashkind’s balloon atrial septostomy were the crowning achievements of the two decades from 1955 to the mid 1970s.


Down Syndrome Atrial Septal Defect Ventricular Septal Defect Open Heart Surgery Rheumatic Fever 
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Additional References and Notes

  1. 123.
    Varghese PJ, Celermajer J, Izukawa T, Haller JA Jr, Rowe RD. Cardiac catheterisation in the newborn: experience with 100 cases. Pediatrics 1969; 44: 24–29.PubMedGoogle Scholar
  2. 124.
    Rudolph AM, Heymann MA. The circulation of the fetus in utero. Methods for studying distribution of blood flow, cardiac output and organ blood flow. Circ Res 1967 21: 163184.Google Scholar
  3. 125.
    Rudolph AM, Yuan S. Response of the pulmonary vasculature to hypoxia and H+ ion concentration changes. J Clin Inv 1966; 45: 399–411.CrossRefGoogle Scholar
  4. 126.
    Friedman WF, Pool PE, Jacobowitz D, Seagren SC, Braunwald E. Sympathetic innervation of the developing rabbit heart: Biochemical and histochemical comparisons of fetal, neonatal and adult rabbit myocardium. Circulation Research 1968; 23: 25–32.PubMedCrossRefGoogle Scholar
  5. 127.
    Smith DW Recognizable patterns of human malformation: genetic embryologic and clinical aspects. Philadelphia: Saunders, 1970.Google Scholar
  6. 127a.
    Smith DW, Jones KL. Smith’s recognisable patterns of human malformations. 4th ed. Philadelphia Saunders 1988.Google Scholar
  7. 128.
    Rosenquist GC, De Haan RL. Migration of precardiac cells in the chick embryo: A radioautographic study. Carnegie Contributions Embryology 1966; 38: 111–115.Google Scholar
  8. 129.
    Pexieder T. Cell death in the morphogenesis and teratogenesis of the heart. Adv Anat Embryol Cell Biol 1975; 51: 1–100.Google Scholar
  9. 130.
    Rychter Z. Experimental morphology of the aortic arches and the heart loop in chick embryos. Adv Morphogen 1962; 2: 333–371.Google Scholar
  10. 131.
    Clark EB, Hu N. Developmental hemodynamic changes in the chick embryo stages 18 to 27. Circ Res 1983; 51: 810–815.CrossRefGoogle Scholar
  11. 132.
    Wilson JG, Warkany J. Aortic arch and cardiovascular anomalies in the offspring of vitamin A deficient rats. Pediatrics 1948; 1: 462–468.PubMedGoogle Scholar
  12. 133.
    Fox MH, Goss CM. Experimentally produced malformations of the heart and great vessels in rat fetuses. Anat Rec 1957; 129: 309–331.PubMedCrossRefGoogle Scholar
  13. 134.
    Kalter H, Warkany J. Experimental production of congenital malformations in mammals by metabolic procedures. Physiol Rev 1959; 39: 69–115.PubMedGoogle Scholar
  14. 135.
    Swan C, Tostevin AL, Moore B, Mayo H, Barham Black GH. Congenital defects in infants following infectious diseases during pregnancy, with special reference to relationship between German measles and cataract, deaf mutism, heart disease and microcephaly, and to period of pregnacy in which occurrence of rubella is followed by congenital abnormalities. Med J Austr 1943; 2: 201–210.Google Scholar
  15. 136.
    Rowe RD. Maternal rubella and pulmonary artery stenosis. Report of eleven cases. Pediatrics 1963; 32: 180–185.Google Scholar
  16. 137.
    Lenz W, Knapp K. Fetal malformations due to thalidomide. German Med Monthly 1962; 7: 253–258.Google Scholar
  17. 138.
    Taussig HB. A study of the German outbreak of phocomelia-The Thalidomide Syndrome. JAMA 1962; 180: 1106–1114.PubMedCrossRefGoogle Scholar
  18. 139.
    Fraser FC, Lenz W, Warkany J, Kelsey FO, Heshka T, Stephens TD, Brent RL, Holmes LB. Thalidomide Symposium. Teratology 1988; 38: 201–241.PubMedCrossRefGoogle Scholar
  19. 140.
    Lipson AH. Thalidomide retrospective: What did the clinical teratologist learn? Teratology 1992; 46: 411–413.PubMedCrossRefGoogle Scholar
  20. 141.
    Lammer EJ, Chen DT, Hoar RM, et al. Retinoic acid embryopathy. New Eng J Med 1985; 313: 837–841.PubMedCrossRefGoogle Scholar
  21. 142.
    Williams JCP, Barratt-Boyes BG, Lowe JB. Supravalvar aortic stenosis. Circulation 1961; 24: 1311–1318.PubMedCrossRefGoogle Scholar
  22. 143.
    Black JA, Bonham Carter RE. Association between aortic stenosis, peripheral pulmonary stenosis, mental retardation, and similar facial appearance. Lancet 1963; 2: 745–748.PubMedCrossRefGoogle Scholar
  23. 144.
    Beuren AJ, Schulze C, Eberle P, Harmanz D, Apitz A. The syndrome of supravalvar aortic stenosis, peripheral pulmonary stenosis, mental retardation, and similar facial appearance. Am J Cardiol 1964; 13: 471–483.PubMedCrossRefGoogle Scholar
  24. 145.
    Ewart AK, Morris CA, Atkinson D, et al. Hemizygosity at the elastin locus in a developmental disorder, Williams syndrome. Nature Genet 1993; 5: 11–16.PubMedCrossRefGoogle Scholar
  25. 146.
    Mitchell SC, Sellman AH, Westphal MC, Park J. Etiologic correlates in a study of congenital heart disease in 56,109 live births. Am J Cardiol 1971; 23: 653–657.CrossRefGoogle Scholar
  26. 147.
    Polani PE, Campbell M. An aetiologic study of congenital heart disease. Ann Hum Genet 1955; 19: 209–230.PubMedCrossRefGoogle Scholar
  27. 148.
    Lamy M, De Grouchy J, Schweisguth O. Genetic and non-genetic factors in the etiology of congenital heart disease: A study of 1188 cases. Am J Hum Genet 1957; 9: 17–41.PubMedGoogle Scholar
  28. 149.
    Patterson DF, Detweiler DK. Hereditary transmission of patent ductus arteriosus in the dog. Am Heart J 1967; 74: 289–290.PubMedCrossRefGoogle Scholar
  29. 150.
    Rowe RD, Uchida IA. Cardiac malformation in mongolism: a prospective study of 184 mongoloid children. Am J Med 1961; 31: 726–735.PubMedCrossRefGoogle Scholar
  30. 151.
    Lejeune J, Gauthier M, Turpin R. Etude des chromosomes somatiques de neuf enfants mongoliens. Comptes Rend Acad Science Paris 1959; 248: 1721–1722.Google Scholar
  31. 152.
    Kibrick S, Benirschke K Acute aseptic myocarditis and meningoencephalitis in the newborn child infected with Cocksackie virus group B type 3. New Eng J Med 1956; 255: 883–889.PubMedCrossRefGoogle Scholar
  32. 153.
    Goodwin JF, Hollman A, Cleland WP, Teare RD. Obstructive cardiomyopathy simulating aortic stenosis. Brit Heart J 1960; 22: 403–414.PubMedCrossRefGoogle Scholar
  33. 154.
    Johnson DH, Rosenthal A, Nadas AS. A forty-year review of bacterial endocarditis in infancy and childhood. Circulation 1975; 51: 581–588.PubMedCrossRefGoogle Scholar
  34. 155.
    Simcha A, Bonham Carter RE. Paroxysmal atrial tachycardia in infants and children. Lancet 1971; 1: 832–834.PubMedCrossRefGoogle Scholar
  35. 156.
    Kawasaki T. Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in infants and children: Clinical observation in 50 cases. Japan J Allergy 1967; 16: 178–222.Google Scholar
  36. 157.
    Barlow JB, Pocock WA, Marchand P, Denny M. The significance of the late systolic murmur. Am Heart J 1963; 66: 443–452.CrossRefGoogle Scholar
  37. 158.
    Markowitz M, Kuttner AG. Rheumatic Fever. Philadelphia: WB Saunders, 1965. 158a. 2nd edition Markowitz M, Gordis L ibid 1972.Google Scholar
  38. 159.
    Swan H, Zeavin I, Blount SG, Virtue RW. Surgery by direct vision in the open heart during hypothermia. JAMA 1953; 153: 1081–1085.CrossRefGoogle Scholar
  39. 160.
    Bigelow WG. Cold Hearts: The story of hypothermia and the pacemaker in heart surgery. Toronto: McClelland and Stewart, 1984.Google Scholar
  40. 161.
    Lillehei CW, Cohen M, Warden HE, Varco RL. The direct vision intracardiac correction of congenital anomalies by controlled cross circulation. Results in thirty two patients with ventricular septal defects, tetralogy of Fallot, and atrioventricular communis defects. Surg 1955; 38: 11–29.Google Scholar
  41. 162.
    Gibbon JH Jr. Application of a mechanical heart and lung apparatus to cardiac surgery. Minnesota Med 1954; 37: 171–185.PubMedGoogle Scholar
  42. 163.
    Hewitt RL, Creech O Jr. History of the pump oxygenator. Arch Surg 1966; 93: 680–696.PubMedCrossRefGoogle Scholar
  43. 164.
    Kirklin JW, DuShane JW, Patrick RT, Donald DE, Hetzel PS, Harshbarger HG, Wood EH. Intracardiac surgery with the aid of a mechanical pump-oxygenator system (Gibbon type): Report of eight cases. Proc Staff Meetings Mayo Clin 1955; 30: 201–206.Google Scholar
  44. 165.
    Lev M. The architecture of the conduction system in congenital heart disease. I. Common atrioventricular orifice. Arch Path 1958; 65: 174–191.Google Scholar
  45. 166.
    Hutchins GM. Coarctation of the aorta as a branch-point of the ductus arteriosus. Am J Path 1971; 63: 203–209.PubMedGoogle Scholar
  46. 167.
    Roberts WC. Anatomically isolated aortic valvular disease: The case against its being of rheumatic etiology. Am J Med 1970; 49: 151–159.PubMedCrossRefGoogle Scholar
  47. 168.
    Campbell M, Neill C, Suzman S. The prognosis in atrial septal defect. Brit Med J 1957; 1: 1375–1383.PubMedCrossRefGoogle Scholar
  48. 169.
    Watson H. Natural history of Ebstein’s anomaly of the tricuspid valve in children and adolescents: An international cooperative study of 505 cases. Brit Heart J 1974; 36: 417–427.CrossRefGoogle Scholar
  49. 170.
    Evans JR, Rowe RD, Keith JD. Spontaneous closure of ventricular septal defects. Circulation 1960; 22: 1044–1054.PubMedCrossRefGoogle Scholar
  50. 171.
    Nadas AS, Ellison RC, Weidman WH editors. Report from the Joint Study of the Natural History of Congenital Heart Defects: Pulmonary stenosis, aortic stenosis, ventricular septal defect. Clinical course and indirect assessment. Circulation 1977; 56 (suppl): 1–87.Google Scholar
  51. 172.
    Morriss JH, McNamara DG. Residua, sequelae, and complications of surgery for congenital heart disease. In: Postoperative congenital heart disease. Rosenthal A, Sonnenblick EH, Lesch M editors. New York, Grune and Stratton 1975: 3–27.Google Scholar
  52. 172a.
    Keane JF, Williams R, Treves S, Rosenthal A. Assessment of the postoperative patient by noninvasive techniques. ibid 1975: 81–98.Google Scholar
  53. 173.
    Senning A. Surgical correction for transposition of the great vessels. Surg 1959; 45: 966–972.Google Scholar
  54. 174.
    Mustard WT. Successful two-stage correction of transposition of the great vessels. Surg 1964; 55: 469–472.Google Scholar
  55. 175.
    Rashkind WJ, Miller WW Creation of an atrial septal defect without thoracotomy: A palliative approach to complete transposition of the great arteries. JAMA 1966; 196: 991–992.PubMedCrossRefGoogle Scholar
  56. 176.
    McNamara DG. Twenty-five years of progress in the medical treatment of pediatric and congenital heart disease. J Am Coll Cardiol 1983; 1: 264–273.PubMedCrossRefGoogle Scholar
  57. 177.
    Cheng TO. Percutaneous balloon valvuloplasty Cheng TO editor New York Igaku-Shoin 1992.Google Scholar
  58. a. Anderson, R.H., Becker A. E., Anatomy and Pathology of Valvular Stenosis. In: Cheng ibid p. 12–39Google Scholar
  59. 178.
    Ross DN, Somerville J. Correction of pulmonary atresia with a homograft aortic valve. Lancet 1966; 2: 1446–1447.PubMedCrossRefGoogle Scholar
  60. 179.
    Rastelli GC, Wallace RB, Ongley PA. Complete repair of transposition of the great arteries with pulmonary stenosis. A review and report of a case using a new surgical technique. Circulation 1969; 39: 83–95.PubMedCrossRefGoogle Scholar
  61. 180.
    Lowe JE, German LD. Cardiac pacemakers and cardiac conduction system abnormalities. In: Surgery of the Chest. Sabiston DC, Spencer FC, editors. 5th ed. Philadelphia, WB Saunders, 1990: 1597–1634.Google Scholar
  62. 181.
    Gillette PC, Garson A Jr. Pediatric arrhythmias: electrophysiology and pacing. Philadelphia, WB Saunders 1990.Google Scholar
  63. 182.
    Rastelli GC, Ongley PA, Kirklin JW McGoon DC. Surgical repair of the complete form of persistent common atrioventricular canal. J Thorac Cardiovasc Surg 1968; 55: 299308.Google Scholar
  64. 183.
    Fontan F, Baudet E. Surgical repair of tricuspid atresia. Thorax 1971; 26: 240–248.PubMedCrossRefGoogle Scholar
  65. 184.
    Gerard R, Lasry F, Seichter J, Malfroy P, Jouve A. Les criteres electocardiographiques de surcharge ventriculaire droite chez l’enfant. I. Les surcharges systoliques. Arch Mal Coeur Vaiss 1969; 62: 1049–1071.PubMedGoogle Scholar
  66. 185.
    Graham TP, Jarmakani JM, Atwood GF, Canent RV. Right ventricular volume determinations in children. Normal values and observations with volume and pressure overload. Circulation 1973; 47: 144–153.PubMedCrossRefGoogle Scholar
  67. 186.
    Brandt PWT, Clarkson PM, Neutze JM, Barratt-Boyes BG. Left ventricular cineangiography in endocardial cushion defect (persistent common atrioventricular canal). Austr J Radiol 1972; 16: 367–376.CrossRefGoogle Scholar
  68. 187.
    Bargeron LM, Elliott LP, Soto B, Bream PR, Currey GC. Axial angiography in congenital heart disease. Section I. Concept, technical and anatomical considerations. Circulation 1977; 56: 1075–1083.PubMedCrossRefGoogle Scholar
  69. 188.
    Fyler DC, Buckley LP, Hellenbrand WE, Cohn HE. Report of the New England Regional Infant Cardiac Program. Pediatrics 1980; 65 (suppl): 375–461.Google Scholar
  70. 189.
    Lewis BS, Gotsman MS. Natural history of rheumatic heart disease in childhood. In: Rheumatic valvular disease in children. Borman JB, Gotsman MS editors Berlin Springer Verlag 1980: 59–71.CrossRefGoogle Scholar
  71. 190a.
    Paul ATS Closed mitral commisurotomy in children. ibid 1980:126–148.Google Scholar
  72. 190.
    Thomas CB, France R. A preliminary report of the prophylactic use of sulfanilamide in patients susceptible to rheumatic fever. Bull Johns Hopkins Hosp 1939; 64: 67–69.Google Scholar
  73. 191.
    Ash R The first 10 years of rheumatic infection in childhood. Am Heart J 1948; 36: 89–93.PubMedCrossRefGoogle Scholar
  74. 192.
    Ten-year report by the Rheumatic Fever Working Party. The natural history of rheumatic fever and rheumatic heart disease. Circulation 1965; 32: 457–476.Google Scholar
  75. 193.
    Coburn AF, Salicylate therapy in rheumatic fever. A rational technique. Bull Johns Hopkins Hosp 1943; 73: 435–464.Google Scholar
  76. 194.
    Odell JA, Vosloo SM. Valvular surgery in children. In: Valvular heart disease. Zaibag MA, Duran CMG editors New York Marcel Dekker 1994: 635–656.Google Scholar
  77. 195.
    Ayoub EM, Barret DJ, Maclaren NK, Kricher P. Association of class II human histocompatibility leucocyte antigens with rheumatic fever. J Clin Inv 1986; 77: 2019–2026.CrossRefGoogle Scholar
  78. 196.
    Dajani AS, Bisno AL, Kyung JC et al. Prevention of rheumatic fever. A statement for health professionals by the committe on rheumatic fever, endocarditis and Kawasaki disease of the Council on Cardiovascular Disease in the Young. Circulation 1988; 78: 1082–1086.CrossRefGoogle Scholar
  79. 197.
    Osier W. On a remarkable heart murmur heard at a distance from the chest wall Can Med Surg J 1879–1880; 8:518–519.Google Scholar
  80. 198.
    Jeresaty RM. Mitral valve prolapse. New York: Raven Press, 1979.Google Scholar
  81. 199.
    Barlow JB, Bosman CK, Pocock WA et al Late systolic murmurs and non-ejection (mid-late) systolic clicks: an analysis of 90 patients Br Heart J 1968; 30: 203–218.Google Scholar
  82. 200.
    Schwartz DC, Daoud G, Kaplan S. Dysfunction of the mitral apparatus in children. Am J Cardiol (abst) 1968; 21: 114.CrossRefGoogle Scholar
  83. 201.
    Sahn DJ, Wood J, Allen HD, et al. Echocardiographic spectrum of mitral valve motion in children with and without mitral valve prolapse: the nature of false postive diagnosis Am J Cardiol 1977; 39: 422–431.Google Scholar
  84. 202.
    Truett J, Cornfield J, Kannel W. A multivariate analysis of the risk of coronary heart disease in Framingham. J Chron Dis 1967. 20: 511–524.PubMedCrossRefGoogle Scholar
  85. 203.
    White PD. The tardy growth of preventive cardiology. Am J Cardiol 1972; 29: 886–888.PubMedCrossRefGoogle Scholar
  86. 204.
    Lauer RM, Connor WE, Leaverton PE, Reiter MA, Clarke WR. Coronary heart disease risk factors in school children-The Muscatine study. J Pediatr. 1975; 86: 697–702.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 1995

Authors and Affiliations

  • Catherine A. Neill
    • 1
  • Edward B. Clark
    • 2
  1. 1.Johns Hopkins Medical InstitutionsBaltimoreUSA
  2. 2.Rochester School of MedicineRochesterUSA

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