The Dawn of Therapy 1936–1955

  • Catherine A. Neill
  • Edward B. Clark
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 163)


The age of therapy dawned only two years after the publication of Abbott’s Atlas. Dr William Gross, at that time a surgical Resident at the Children Hospital in Boston, ligated a patent ductus arteriosus on August 26 1938 [84]. The concept of clinicophysiologic correlation had already been introduced, but the advent of surgery gave diagnosis an impetus and immediacy which had been lacking before. Repair of aortic coarctation and the development of the Blalock Taussig shunt followed soon afterwards, and by the end of the 1940s closed heart surgery was available for many defects. The period from 1936 to 1955 was the dawn of therapy, the beginning of a completely new way of viewing congenital heart defects as capable of diagnosis, understanding, and treatment.


Congenital Heart Disease Cardiac Catheterisation Patent Ductus Arteriosus Atrial Septal Defect Pulmonary Blood Flow 
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Copyright information

© Springer Science+Business Media Dordrecht 1995

Authors and Affiliations

  • Catherine A. Neill
    • 1
  • Edward B. Clark
    • 2
  1. 1.Johns Hopkins Medical InstitutionsBaltimoreUSA
  2. 2.Rochester School of MedicineRochesterUSA

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