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Small-Angle Neutron Scattering of Biological Macromolecular Complexes Consisting of Proteins and Nucleic Acids

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Modern Aspects of Small-Angle Scattering

Part of the book series: Nato ASI Series ((ASIC,volume 451))

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Abstract

Small-angle neutron scattering is a convenient, non invasive tool for studying the structures of biological macromolecules in solution. In particular, molecules consisting of several classes of matter, e.g. proteins, nucleic acids or lipids, can be advantageously investigated using the conventional solvent or the more recent spin contrast variation techniques, often together with specific deuteration. This chapter is dedicated to the “classical” methods, including label triangulation. Applications of small-angle neutron scattering to the study of viruses and of molecules and organelles involved in gene expression are presented.

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May, R.P. (1995). Small-Angle Neutron Scattering of Biological Macromolecular Complexes Consisting of Proteins and Nucleic Acids. In: Brumberger, H. (eds) Modern Aspects of Small-Angle Scattering. Nato ASI Series, vol 451. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-8457-9_14

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  • DOI: https://doi.org/10.1007/978-94-015-8457-9_14

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-4499-0

  • Online ISBN: 978-94-015-8457-9

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