Abstract
The adaptation of lasers to therapy for cardiovascular diseases is in its infancy, but the use of lasers to treat important clinical problems and improve the overall care of patients is rapidly increasing. The ability to precisely and predictably ablate abnormal vascular tissues or atherosclerotic lesions, thus enhancing the accuracy of vessel recanalization is now a clinical reality. Early empirical studies of the effects of laser energy on cardiovascular tissue have demonstrated the potential for a variety of therapeutic advances including angioplasty, valvular repair and ablation of arrhythmogenic foci. However, progress toward clinical applications has been impeded by technical difficulties and by lack of specific information about laser energy interaction with cardiovascular tissue. It has become apparent that the effects of laser energy on tissue differ widely according to the laser parameters and the specific characteristics of the tissue.
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References
R. R. Alfano et al., “Fluorescence spectra from cancerous and normal human breast and lung tissues”, IEEE J.Quantum Electron. QE-23, 1806–1811 (1987)
P.S. Andersson et al., “Autofluorescence of various rodent tissues and human skin tumour samples”, Lasers in Medical Science, vol.2, 1987
S. Montan et al., “Multicolor imaging and contrast enhancement in cancer tissue localization using laser induced fluorescence in hematoporphyrin derivative bearing tissue”, Opt. Lett.10, 56–58(1985)
C. Kittrel et al., “Diagnosis of fibrous arterial atherosclerosis using fluorescence”, Appl. Opt. 24, 2280–2281 (1985)
M.R. Prince et al., “Preferential light absorption in atheromas in vitro”, J.Clin.Invest. 78, 295–302 (1986)
E.J. Gaffney et al., “Correlation of fluorescence emission with plaque content and intimal thickness of atherosclerotic coronary arteries”, Lasers Surg. Med. 9, 215–228 (1989)
K. O’Brien et al., “Development and evaluation of spectral classification algorithms for fluorescence guided laser angioplasty”, IEEE Trans. Biomed. Eng., BE-36, 424–429, (1989)
F.W. Cutruzzola et al., “Changes in laser induced arterial fluorescence during ablation of atherosclerotic plaque”, Lasers Surg. Med. 9, 109–116 (1989)
L.I. Deckelbaum et al., “Fluorescence spectroscopy guidance of laser ablation of atherosclerotic plaque”, Lasers Surg. Med. 9, 205–214 (1989)
M. Sartori et al., “Autofluorescence maps of atherosclerotic human arteries-a new technique in medical imaging”, IEEE J. Quantum Electr. QE-23, 1794- (1987)
P.S. Andersson et al., “Multispectral system for medical fluorescence imaging”, IEEE J. Quantum Electron. QE-23, 1798–1805 (1987)
C.C. Hoyt et al., “Remote biomedical spectroscopic imaging of human arteri wall”, Lasers Surg. Med. 8, 1–9(1988)
R.H. Clarke et al., “Laser Ramman spectroscopy of atherosclerotic lesions ir human coronary artery segments”, Appl. Opt. 27, 4799–4800
A. van Hoeck et al., “Ultrasensitive time resolved polarized fluorescence spectroscopy as a tool in biology and medicine”, IEEE J. Quantum Electr. Q 23, 1812–1820 (1987)
J.B. Laudenslager, “Excimer lasers adapt to angioplasty”, Laser Focus 5, 57–68 (1988)
M.B. Leon et al., “Human arterial surface fluorescence: Atherosclerotic plaque identification and effects of laser atheroma ablation”, J. Am.Coll.Cardiol. 12, 94–102(1988)
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© 1994 Springer Science+Business Media Dordrecht
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Papazoglou, T.G. (1994). Laser induced fluorescence as a tool for atherosclerotic tissue characterization during Excimer laser aided ablation. In: Laude, L.D. (eds) Excimer Lasers. NATO ASI Series, vol 265. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-8104-2_31
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DOI: https://doi.org/10.1007/978-94-015-8104-2_31
Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-4395-5
Online ISBN: 978-94-015-8104-2
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